Title : Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1.

Pub. Date : 2011 Jun 15

PMID : 21463258






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TDP (tyrosyl-DNA phosphodiesterase) 1 catalyses the hydrolysis of phosphodiester linkages between a DNA 3" phosphate and a tyrosine residue as well as a variety of other DNA 3" substituents, and has been implicated in the repair of covalent complexes involving eukaryotic type IB topoisomerases. Tyrosine tyrosyl-DNA phosphodiesterase 1 Homo sapiens