Title : Innate T-αβ lymphocytes as new immunological components of anti-tumoral "off-target" effects of the tyrosine kinase inhibitor dasatinib.

Pub. Date : 2020 Feb 24

PMID : 32094501






1 Functional Relationships(s)
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1 Lastly, in patients administered with dasatinib for the treatment of BCR-ABL-positive leukemias, we provided the proof of concept that the kinase inhibitor also influences the two innate T-cell subsets in humans, as attested by their increased frequency in the peripheral blood. Dasatinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens