Tyrosine

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







361 Article(s)
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51 28087699 Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase. 2017 Mar 3 1
52 28279034 [Clinical significance of cytogenetic monitoring in chronic myeloid leukemia]. 2017 Feb 14 1
53 28288113 Germline mutations in ABL1 cause an autosomal dominant syndrome characterized by congenital heart defects and skeletal malformations. 2017 Apr 1
54 28378189 Cleavage and phosphorylation: important post-translational modifications of galectin-3. 2017 Jun 1
55 28428613 Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop. 2017 Apr 20 1
56 28486134 Abl Regulates Planar Polarized Junctional Dynamics through β-Catenin Tyrosine Phosphorylation. 2017 May 8 1
57 28578803 Head and neck cancer cell radiosensitization upon dual targeting of c-Abl and beta1-integrin. 2017 Sep 2
58 28666867 Enhancement of TGF-β-induced Smad3 activity by c-Abl-mediated tyrosine phosphorylation of its coactivator SKI-interacting protein (SKIP). 2017 Aug 26 1
59 29022905 c-Abl-mediated Drp1 phosphorylation promotes oxidative stress-induced mitochondrial fragmentation and neuronal cell death. 2017 Oct 12 1
60 29066624 Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9. 2017 Dec 29 5
61 26866052 Expression, purification, crystallization and X-ray data collection for RAS and its mutants. 2016 Mar 2
62 27018250 Functional interaction between nonreceptor tyrosine kinase c-Abl and SR-Rich protein RBM39. 2016 Apr 22 1
63 27078848 CRKL mediates EML4-ALK signaling and is a potential therapeutic target for ALK-rearranged lung adenocarcinoma. 2016 May 17 1
64 27161995 Parallel Chemical Protein Synthesis on a Surface Enables the Rapid Analysis of the Phosphoregulation of SH3 Domains. 2016 Jun 13 1
65 27228340 MicroRNA-1301-Mediated RanGAP1 Downregulation Induces BCR-ABL Nuclear Entrapment to Enhance Imatinib Efficacy in Chronic Myeloid Leukemia Cells. 2016 1
66 27348587 Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration. 2016 Aug 1 1
67 27757426 TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. 2016 Apr 3
68 25043303 Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity. 2015 May 14 1
69 25082234 HAUSP compartmentalization in chronic myeloid leukemia. 2015 Apr 1
70 25249015 Grb10 is involved in BCR-ABL-positive leukemia in mice. 2015 Apr 2
71 25527332 The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear. 2015 Jan 1
72 25694432 The interaction of protein-tyrosine phosphatase α (PTPα) and RACK1 protein enables insulin-like growth factor 1 (IGF-1)-stimulated Abl-dependent and -independent tyrosine phosphorylation of PTPα. 2015 Apr 10 2
73 25770215 Role for Tyrosine Phosphorylation of A-kinase Anchoring Protein 8 (AKAP8) in Its Dissociation from Chromatin and the Nuclear Matrix. 2015 Apr 24 1
74 25795725 c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury. 2015 May 15 2
75 25821558 HSP90 inhibitor AUY922 induces cell death by disruption of the Bcr-Abl, Jak2 and HSP90 signaling network complex in leukemia cells. 2015 Jan 1
76 25999467 Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. 2015 Sep 3
77 26126715 The kinase ABL phosphorylates the microprocessor subunit DGCR8 to stimulate primary microRNA processing in response to DNA damage. 2015 Jun 30 2
78 26134485 Site Selective Azo Coupling for Peptide Cyclization and Affinity Labeling of an SH3 Protein. 2015 Aug 19 1
79 26217035 c-Abl-mediated tyrosine phosphorylation of JunB is required for Adriamycin-induced expression of p21. 2015 Oct 1 4
80 26235616 c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells. 2015 Aug 11 1
81 26310847 Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation. 2015 Aug 27 1
82 26697169 Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function. 2015 Dec 2
83 23542172 The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer. 2014 Mar 13 1
84 24317448 BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP. 2014 Jun 1
85 24378532 PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway. 2014 Apr 1
86 24412932 c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease. 2014 Jun 1 2
87 24445143 IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation. 2014 May 2
88 24455116 Imatinib in chronic myeloid leukemia: an overview. 2014 Jan 2 1
89 24475245 Oligomerization and phosphorylation dependent regulation of ArgBP2 adaptive capabilities and associated functions. 2014 1
90 24569990 Inhibiting tyrosine phosphorylation of protein kinase Cδ (PKCδ) protects the salivary gland from radiation damage. 2014 Apr 11 5
91 24759597 SAHA and S116836, a novel tyrosine kinase inhibitor, synergistically induce apoptosis in imatinib-resistant chronic myelogenous leukemia cells. 2014 Jul 1
92 24786396 The c-Abl inhibitor, nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease. 2014 May 2 1
93 24836440 BCR-ABL affects STAT5A and STAT5B differentially. 2014 1
94 24913448 LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia. 2014 Jul 30 1
95 25201268 Electrochemical evaluation of Abelson tyrosine-protein kinase 1 activity and inhibition by imatinib mesylate and danusertib. 2014 Oct 3 1
96 25264277 Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27(KIP1) as a consequence of c-Abl inhibition. 2014 Nov 15 2
97 22976128 Imatinib-dependent tyrosine phosphorylation profiling of Bcr-Abl-positive chronic myeloid leukemia cells. 2013 Mar 1
98 23233201 PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells. 2013 Feb 2
99 23318434 Dual regulation of Myc by Abl. 2013 Nov 7 5
100 23325923 c-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity. 2013 Apr 2