Pub. Date : 2015 Sep
PMID : 25999467
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. | Tyrosine | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 2 | Here we report that ABL phosphorylates tyrosine 137 of H-, K-, and NRAS. | Tyrosine | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 3 | Increased RIN1 levels enhanced HRAS-Tyr(137) phosphorylation by nearly 5-fold, suggesting that RAS-stimulated RIN1 can drive ABL-mediated RAS modification in a feedback circuit. | Tyrosine | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |