Guanosine Diphosphate

succinate-CoA ligase GDP/ADP-forming subunit alpha ; Homo sapiens







94 Article(s)
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1 33876404 Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation. 2021 Aug 1
2 34445383 Research Advances in Heterotrimeric G-Protein α Subunits and Uncanonical G-Protein Coupled Receptors in Plants. 2021 Aug 12 3
3 34769272 Heterotrimeric G Proteins in Plants: Canonical and Atypical Gα Subunits. 2021 Oct 31 2
4 31930311 Plant receptor-like kinase signaling through heterotrimeric G-proteins. 2020 Mar 12 2
5 31967346 Ric-8A, a GEF, and a Chaperone for G Protein α-Subunits: Evidence for the Two-Faced Interface. 2020 Mar 1
6 32092921 Oocyte Maturation in Starfish. 2020 Feb 19 1
7 32103024 Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1. 2020 Feb 26 1
8 32662237 A simple open source bioinformatic methodology for initial exploration of GPCR ligands' agonistic/antagonistic properties. 2020 Aug 1
9 32786510 GDP Release from the Open Conformation of Gα Requires Allosteric Signaling from the Agonist-Bound Human β2 Adrenergic Receptor. 2020 Aug 24 5
10 31624147 Large-scale conformational rearrangement of the α5-helix of Gα subunits in complex with the guanine nucleotide exchange factor Ric8A. 2019 Nov 22 2
11 29777099 Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. 2018 May 18 1
12 30406994 A Residue outside the Binding Site Determines the Gα Binding Specificity of GoLoco Motifs. 2018 Nov 27 1
13 28223697 Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses. 2017 Feb 22 5
14 28760338 Structural dynamics of Giα protein revealed by single molecule FRET. 2017 Sep 23 1
15 26667172 Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection. 2016 Jan 15 1
16 26996924 Invited review: Activation of G proteins by GTP and the mechanism of Gα-catalyzed GTP hydrolysis. 2016 Aug 3
17 27483005 Computational Simulation of the Activation Cycle of Gα Subunit in the G Protein Cycle Using an Elastic Network Model. 2016 7
18 27498775 The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer. 2016 Sep 1
19 27558716 Nanosecond Dynamics of Gαi1 Bound to Nucleotides or Ric-8A, a Gα Chaperone with GEF Activity. 2016 Aug 23 2
20 27871057 Mechanistic insights into GPCR-G protein interactions. 2016 Dec 1
21 27911799 Mechanism of the intrinsic arginine finger in heterotrimeric G proteins. 2016 Dec 13 1
22 25414258 Pivotal role of extended linker 2 in the activation of Gα by G protein-coupled receptor. 2015 Jan 2 1
23 25480567 Activator of G protein signaling 3 forms a complex with resistance to inhibitors of cholinesterase-8A without promoting nucleotide exchange on Gα(i3). 2015 Mar 4
24 25605908 The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1. 2015 Feb 3 2
25 25666614 Integration of G protein α (Gα) signaling by the regulator of G protein signaling 14 (RGS14). 2015 Apr 3 2
26 26179037 Evaluating the Activity of Smoothened Toward G Proteins Using [³⁵S]Guanosine 5'-(3-O-thio)triphosphate ([³⁵S]GTPγS). 2015 1
27 23771857 Backbone resonance assignments for G protein α(i3) subunit in the GDP-bound state. 2014 Oct 1
28 24292645 Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release. 2014 Jan 1
29 24583286 Implications of non-canonical G-protein signaling for the immune system. 2014 Jun 2
30 25036778 A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation. 2014 Jul 17 1
31 23200849 Gα(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells. 2013 Mar 3
32 23415100 Fine-tuning of GPCR signals by intracellular G protein modulators. 2013 1
33 23576747 Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis. 2013 Apr 16 1
34 23626793 A high throughput screen for RGS proteins using steady state monitoring of free phosphate formation. 2013 1
35 24386514 Structural Aspects of GPCR-G Protein Coupling. 2013 Sep 1
36 22167191 G-protein signaling modulator-3 regulates heterotrimeric G-protein dynamics through dual association with Gβ and Gαi protein subunits. 2012 Feb 10 3
37 22274999 Backbone resonance assignments for G protein α(i3) subunit in the GTP-bound state. 2012 Oct 2
38 22952234 Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi. 2012 Oct 26 8
39 21375271 Coupling efficiency of rhodopsin and transducin in bicelles. 2011 Apr 19 1
40 21390270 Nucleotide binding switches the information flow in ras GTPases. 2011 Mar 2
41 21853086 The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1. 2011 1
42 20075078 G proteins in reverse mode: receptor-mediated GTP release inhibits G protein and effector function. 2010 Mar 12 1
43 19686126 Functional expression of chemoreceptors with the help of a Guanine nucleotide exchange factor. 2009 Jul 1
44 19703944 GDP-GTP exchange processes of G{alpha}i1 protein are accelerated/decelerated depending on the type and the concentration of added detergents. 2009 Dec 1
45 19760664 Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins. 2009 Nov 2
46 19783621 N terminus of type 5 adenylyl cyclase scaffolds Gs heterotrimer. 2009 Dec 3
47 19820068 Two Galpha(i1) rate-modifying mutations act in concert to allow receptor-independent, steady-state measurements of RGS protein activity. 2009 Dec 1
48 18537558 State-selective binding peptides for heterotrimeric G-protein subunits: novel tools for investigating G-protein signaling dynamics. 2008 Jun 2
49 18541531 Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3. 2008 Aug 22 6
50 19513240 A sweet cycle for Arabidopsis G-proteins: Recent discoveries and controversies in plant G-protein signal transduction. 2008 Dec 6