Guanosine Diphosphate

⇄

succinate-CoA ligase GDP/ADP-forming subunit alpha ; Homo sapiens







94 Article(s)
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Pub. Year
#Total Relationships
51 17430994 Receptor-mediated activation of heterotrimeric G-proteins: current structural insights. 2007 Aug 2
52 17644194 Modulating G-protein-coupled receptors: from traditional pharmacology to allosterics. 2007 Aug 2
53 17854654 Structural basis of effector regulation and signal termination in heterotrimeric Galpha proteins. 2007 1
54 17962409 Galpha Gbetagamma dissociation may be due to retraction of a buried lysine and disruption of an aromatic cluster by a GTP-sensing Arg Trp pair. 2007 Nov 2
55 16407201 Gbetagamma inhibits Galpha GTPase-activating proteins by inhibition of Galpha-GTP binding during stimulation by receptor. 2006 Feb 24 1
56 16892066 Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins. 2006 Sep 1
57 16923326 Structural basis of function in heterotrimeric G proteins. 2006 May 4
58 17011013 Rhodopsin-transducin coupling: role of the Galpha C-terminus in nucleotide exchange catalysis. 2006 Dec 1
59 17053066 Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway. 2006 Oct 31 1
60 15665133 Determination of the activation volume of PLCbeta by Gbeta gamma-subunits through the use of high hydrostatic pressure. 2005 Apr 2
61 15983037 Motion of carboxyl terminus of Galpha is restricted upon G protein activation. A solution NMR study using semisynthetic Galpha subunits. 2005 Sep 2 2
62 16004878 Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange. 2005 Jul 1
63 16051611 A peptide core motif for binding to heterotrimeric G protein alpha subunits. 2005 Sep 16 1
64 16190775 Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins. 2005 Oct 6 1
65 16225870 A bifunctional Galphai/Galphas modulatory peptide that attenuates adenylyl cyclase activity. 2005 Oct 24 1
66 14656218 Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. 2004 Mar 15 2
67 15007073 Sequence of interactions in receptor-G protein coupling. 2004 Jun 4 2
68 15081806 Molecular dynamics simulations of transducin: interdomain and front to back communication in activation and nucleotide exchange. 2004 Apr 30 2
69 15271992 Perturbing the linker regions of the alpha-subunit of transducin: a new class of constitutively active GTP-binding proteins. 2004 Sep 17 1
70 15313557 Regulation of chemokine-induced lymphocyte migration by RGS proteins. 2004 1
71 15368366 Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate. 2004 Oct 1 1
72 15488186 Characterization of GRK2 RH domain-dependent regulation of GPCR coupling to heterotrimeric G proteins. 2004 1
73 12509430 Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor. 2003 Mar 7 1
74 12598904 Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant. 2003 Mar 2
75 12719437 Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha. 2003 Jun 27 1
76 12831845 Albumin: a Galpha(s)-specific guanine nucleotide dissociation inhibitor and GTPase activating protein. 2003 Jul 15 1
77 12834345 The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution. 2003 Jul 8 1
78 14609727 The [35S]GTPgammaS binding assay: approaches and applications in pharmacology. 2003 Dec 12 2
79 12146960 Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation. 2002 Aug 6 2
80 11294858 Regulator of G-protein signaling 3 (RGS3) inhibits Gbeta1gamma 2-induced inositol phosphate production, mitogen-activated protein kinase activation, and Akt activation. 2001 Jun 29 3
81 11344266 Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation? 2001 May 22 1
82 11529678 An intramolecular contact in Galpha transducin that participates in maintaining its intrinsic GDP release rate. 2001 Sep 7
83 11583165 Rapid irreversible G protein alpha subunit misfolding due to intramolecular kinetic bottleneck that precedes Mg2+ "lock" after GTP/GDP exchange. 2001 Aug 14 4
84 9891006 Conformational changes at the carboxyl terminus of Galpha occur during G protein activation. 1999 Jan 22 2
85 9892662 A Gsalpha mutant designed to inhibit receptor signaling through Gs. 1999 Jan 19 2
86 10366609 Sequestration of G-protein beta gamma subunits by different G-protein alpha subunits blocks voltage-dependent modulation of Ca2+ channels in rat sympathetic neurons. 1999 Jun 15 1
87 10403517 Kinetic control of guanine nucleotide binding to soluble Galpha(q). 1999 Jul 1 2
88 10611444 Volatile anesthetics modulate the binding of guanine nucleotides to the alpha subunits of heterotrimeric GTP binding proteins. 1999 Nov 19 1
89 9419378 Gsalpha-selective G protein antagonists. 1998 Jan 6 1
90 9753695 Structural basis of activity and subunit recognition in G protein heterotrimers. 1998 Sep 15 1
91 9159128 Conditional activation defect of a human Gsalpha mutant. 1997 May 27 2
92 8611570 A 50 KDa protein modulates guanine nucleotide binding of transglutaminase II. 1996 Feb 27 6
93 8939752 Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis. 1996 Nov 15 1
94 8039765 [Role of heterotrimeric GTP-binding proteins in cellular signaling]. 1994 Jun 1