| 1 |
32106718 | Montelukast ameliorates doxorubicin-induced cardiotoxicity via modulation of p-glycoprotein and inhibition of ROS-mediated TNF-α/NF-κB pathways. | 2022 Mar |
1 |
| 2 |
35545360 | Astragalus polysaccharides affects multidrug resistance gene 1 and P-glycoprotein 170 in adriamycin nephropathy rats via regulating microRNA-16/NF-κB axis. | 2022 Jan 28 |
1 |
| 3 |
27720963 | Multilayer micro-dispersing system as oral carriers for co-delivery of doxorubicin hydrochloride and P-gp inhibitor. | 2017 Jan |
2 |
| 4 |
29176019 | In vitro modulation of the cytochrome P450 and ABCB1/P-glycoprotein activities of the aqueous extract of Allophylus cominia (L) Sw. leaves. | 2017 Dec 20 |
1 |
| 5 |
26530267 | Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells. | 2016 Jan |
2 |
| 6 |
25581352 | Improved oral absorption of doxorubicin by amphiphilic copolymer of lysine-linked ditocopherol polyethylene glycol 2000 succinate: in vitro characterization and in vivo evaluation. | 2015 Feb 2 |
3 |
| 7 |
24632013 | Protective mechanisms of coenzyme-Q10 may involve up-regulation of testicular P-glycoprotein in doxorubicin-induced toxicity. | 2014 Mar |
5 |
| 8 |
22161812 | Lysophosphatidic acid receptor-3 increases tumorigenicity and aggressiveness of rat hepatoma RH7777 cells. | 2013 Apr |
2 |
| 9 |
23574017 | Effects of 17α-ethynylestradiol-induced cholestasis on the pharmacokinetics of doxorubicin in rats: reduced biliary excretion and hepatic metabolism of doxorubicin. | 2013 Oct |
2 |
| 10 |
23630447 | Genomic profiling reveals the potential role of TCL1A and MDR1 deficiency in chemotherapy-induced cardiotoxicity. | 2013 |
1 |
| 11 |
23770382 | Evaluation of the pharmacokinetics and cardiotoxicity of doxorubicin in rat receiving nilotinib. | 2013 Oct 1 |
1 |
| 12 |
23878263 | Shear stress activation of nuclear receptor PXR in endothelial detoxification. | 2013 Aug 6 |
1 |
| 13 |
22361031 | Encapsulation of P-glycoprotein inhibitors by polymeric micelles can reduce their pharmacokinetic interactions with doxorubicin. | 2012 May |
8 |
| 14 |
21380815 | Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in rats: possible role of CYP3A4 and P-glycoprotein inhibition by myricetin. | 2011 Feb |
1 |
| 15 |
21544726 | Effects of quercetin on the bioavailability of doxorubicin in rats: role of CYP3A4 and P-gp inhibition by quercetin. | 2011 Apr |
1 |
| 16 |
21699081 | Minor effects of the citrus flavonoids naringin, naringenin and quercetin, on the pharmacokinetics of doxorubicin in rats. | 2011 Jun |
2 |
| 17 |
21737631 | P-glycoprotein modulation by valspodar and cyclosporin does not increase tumor uptake of doxorubicin administered via isolated lung perfusion to rats bearing sarcoma lung metastases. | 2011 Jun |
2 |
| 18 |
21822614 | A probable relationship between characteristic accumulation of doxorubicin and P-glycoprotein transporter in rat liver. | 2011 Oct |
1 |
| 19 |
19827298 | Effects of baicalein, an antioxidant, on the bioavailability of doxorubicin in rats: possible role of P-glycoprotein inhibition by baicalein. | 2009 Sep |
2 |
| 20 |
16126379 | Pharmacokinetics of intravenously administered stealth liposomal doxorubicin modulated with verapamil in rats. | 2006 Jan |
1 |
| 21 |
16353156 | Development of multidrug resistance due to multiple factors including P-glycoprotein overexpression under K-selection after MYC and HRAS oncogene activation. | 2006 May 15 |
1 |
| 22 |
16377671 | Involvement of the drug transporters p glycoprotein and multidrug resistance-associated protein Mrp2 in telithromycin transport. | 2006 Jan |
1 |
| 23 |
16483613 | Gender-related differences in expression and function of hepatic P-glycoprotein and multidrug resistance-associated protein (Mrp2) in rats. | 2006 Jun 27 |
1 |
| 24 |
16540558 | Cyclooxygenase-2 rescues rat mesangial cells from apoptosis induced by adriamycin via upregulation of multidrug resistance protein 1 (P-glycoprotein). | 2006 Apr |
4 |
| 25 |
17090397 | Cytotoxicity of doxorubicin bound to poly(butyl cyanoacrylate) nanoparticles in rat glioma cell lines using different assays. | 2006 Nov |
4 |
| 26 |
15937726 | Investigation of the influence of modulation of P-glycoprotein by a multiple dosing regimen of tamoxifen on the pharmacokinetics and toxicodynamics of doxorubicin. | 2005 Nov |
10 |
| 27 |
14744620 | Azithromycin reverses anticancer drug resistance and modifies hepatobiliary excretion of doxorubicin in rats. | 2004 Jan 26 |
1 |
| 28 |
12709333 | Shiga-like toxin II impairs hepatobiliary transport of doxorubicin in rats by down-regulation of hepatic P glycoprotein and multidrug resistance-associated protein Mrp2. | 2003 May |
4 |
| 29 |
14622113 | P-glycoprotein (ABCB1) but not multidrug resistance-associated protein 1 (ABCC1) is induced by doxorubicin in primary cultures of rat astrocytes. | 2003 Nov |
6 |
| 30 |
12113888 | Tissue-specific regulation of expression and activity of P-glycoprotein in adjuvant arthritis rats. | 2002 Jul |
1 |
| 31 |
11724350 | Influence of hypotonic stress on the biliary excretion of doxorubicin in Wistar and TR- rats. | 2001 Jul-Aug |
5 |
| 32 |
11062690 | Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats. | 2000 Sep-Oct |
5 |
| 33 |
10190554 | Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures. | 1999 Mar |
1 |
| 34 |
10368660 | Transport of doxorubicin in mast cell granules and the effect of the calcium antagonist verapamil. | 1999 Mar-Apr |
3 |
| 35 |
10494879 | Contribution of mdr1b-type P-glycoprotein to okadaic acid resistance in rat pituitary GH3 cells. | 1999 Aug |
1 |
| 36 |
9504375 | Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level. | 1998 Feb |
1 |
| 37 |
9525837 | Modulation of doxorubicin concentration by cyclosporin A in brain and testicular barrier tissues expressing P-glycoprotein in rats. | 1998 Mar |
4 |
| 38 |
9721873 | Effect of multidrug resistance modulators on the hepatobiliary disposition of doxorubicin in the isolated perfused rat liver. | 1998 Aug 15 |
1 |
| 39 |
9780140 | P-glycoprotein-mediated efflux transport of anticancer drugs at the blood-brain barrier. | 1998 Oct |
1 |
| 40 |
9210482 | Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment. | 1997 May 15 |
11 |
| 41 |
9395229 | Functional characterization of the rat mdr1b encoded P-glycoprotein: not all inducing agents are substrates. | 1997 Nov |
1 |
| 42 |
8640928 | Differential regulation of mdr genes in response to 2-acetylaminofluorene treatment in cultured rat and human hepatocytes. | 1996 May |
2 |
| 43 |
7475916 | Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes. | 1995 |
1 |
| 44 |
7763297 | In vivo and in vitro evidence for ATP-dependency of P-glycoprotein-mediated efflux of doxorubicin at the blood-brain barrier. | 1995 May 17 |
8 |
| 45 |
7905826 | Constitutive expression of functional P-glycoprotein in rat hepatoma cells. | 1994 Jan 15 |
3 |
| 46 |
7910810 | Establishment and in vivo characterization of multidrug-resistant dunning R3327 rat prostate-carcinoma cell-lines. | 1994 Jun 1 |
2 |
| 47 |
7913321 | P-glycoprotein expression and function in rat hepatocytes in culture. | 1994 Jun 15 |
1 |
| 48 |
21566973 | Doxorubicin enhances transient expression of p-glycoprotein and modulates activity and isoform expression of protein-kinase-C in ah66 rat hepatoma-cells. | 1994 Mar |
1 |
| 49 |
8101494 | Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes. | 1993 Jul 26 |
4 |
| 50 |
8102127 | Differential over-expression of mdr1 genes in multidrug-resistant rat glioblastoma cell lines selected with doxorubicin or vincristine. | 1993 Aug 19 |
1 |