Pub. Date : 2006 Apr
PMID : 16540558
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclooxygenase-2 rescues rat mesangial cells from apoptosis induced by adriamycin via upregulation of multidrug resistance protein 1 (P-glycoprotein). | Doxorubicin | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 2 | Cyclooxygenase-2 rescues rat mesangial cells from apoptosis induced by adriamycin via upregulation of multidrug resistance protein 1 (P-glycoprotein). | Doxorubicin | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 3 | It was shown previously that adenovirus-mediated gene transfer of COX-2 into rat GMC led to increased expression and activity of multidrug resistance protein 1 (MDR-1), a membrane transporter that functions as an efflux pump for chemotherapeutic drugs, including Adriamycin (ADR). | Doxorubicin | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 4 | It was shown previously that adenovirus-mediated gene transfer of COX-2 into rat GMC led to increased expression and activity of multidrug resistance protein 1 (MDR-1), a membrane transporter that functions as an efflux pump for chemotherapeutic drugs, including Adriamycin (ADR). | Doxorubicin | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |