Title : Development of multidrug resistance due to multiple factors including P-glycoprotein overexpression under K-selection after MYC and HRAS oncogene activation.

Pub. Date : 2006 May 15

PMID : 16353156






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclosporin A, a competitive inhibitor of Pgp, increased the intracellular accumulation of DOX and reduced the resistance to it. Doxorubicin ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus