Title : Astragalus polysaccharides affects multidrug resistance gene 1 and P-glycoprotein 170 in adriamycin nephropathy rats via regulating microRNA-16/NF-κB axis.

Pub. Date : 2022 Jan 28

PMID : 35545360






1 Functional Relationships(s)
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1 CONCLUSIONS: APS can regulate the miR-16/NF-kappaB signaling pathway, thereby affecting the levels of MDR1 and P-gp170, and reducing the inflammation in the kidney tissues in the adriamycin nephropathy rats. Doxorubicin ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus