| 1 |
33595097 | IL-17-induced inflammation modulates the mPGES-1/PPAR-γ pathway in monocytes/macrophages. | 2022 May |
1 |
| 2 |
34465013 | Upregulation of prostaglandin E2 by inducible microsomal prostaglandin E synthase-1 in colon cancer. | 2022 Apr |
4 |
| 3 |
34766335 | Effects of microsomal prostaglandin E synthase-1 inhibition on resistance artery tone in patients with end stage kidney disease. | 2022 Apr |
3 |
| 4 |
34798265 | Microsomal prostaglandin E2 synthase-1 and its inhibitors: Molecular mechanisms and therapeutic significance. | 2022 Jan |
4 |
| 5 |
34877656 | Microsomal prostaglandin E synthase-1 is involved in the metabolic and cardiovascular alterations associated with obesity. | 2022 Jun |
2 |
| 6 |
34983695 | Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate-induced colitis in mice lacking microsomal prostaglandin E synthase-1. | 2022 Jan 4 |
4 |
| 7 |
35056712 | Green, Black and Rooibos Tea Inhibit Prostaglandin E2 Formation in Human Monocytes by Inhibiting Expression of Enzymes in the Prostaglandin E2 Pathway. | 2022 Jan 8 |
1 |
| 8 |
35099767 | Inducible Prostaglandin E Synthase as a Pharmacological Target for Ischemic Stroke. | 2022 Jan |
6 |
| 9 |
35105690 | Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis. | 2022 Apr 1 |
2 |
| 10 |
35152061 | Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase. | 2022 Mar 5 |
3 |
| 11 |
35240529 | Rutin hydrate and extract from Castanopsis tribuloides reduces pyrexia via inhibiting microsomal prostaglandin E synthase-1. | 2022 Apr |
1 |
| 12 |
35417776 | Sinomenine increases the methylation level at specific GCG site in mPGES-1 promoter to facilitate its specific inhibitory effect on mPGES-1. | 2022 Apr |
1 |
| 13 |
35466565 | Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors. | 2022 Jun 20 |
1 |
| 14 |
32621176 | Regulation of PGE2 Pathway During Cerebral Ischemia Reperfusion Injury in Rat. | 2021 Oct |
1 |
| 15 |
33049240 | Localization of prostaglandin E2 synthases and E-prostanoid receptors in the spinal cord in a rat model of neuropathic pain. | 2021 Jan 1 |
1 |
| 16 |
33053444 | Prostaglandin E receptors as targets for ischemic stroke: Novel evidence and molecular mechanisms of efficacy. | 2021 Jan |
2 |
| 17 |
33246032 | Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP). | 2021 Feb |
1 |
| 18 |
33292158 | Triazol-phenyl Antipyretic Derivatives Inhibit mPGES-1 mRNA Levels in LPS-Induced RAW 264.7 Macrophage Cells. | 2021 |
5 |
| 19 |
33441600 | Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE2 biosynthesis by sonlicromanol's metabolite KH176m. | 2021 Jan 13 |
2 |
| 20 |
33527033 | Targeting microsomal prostaglandin E synthase 1 to develop drugs treating the inflammatory diseases. | 2021 |
3 |
| 21 |
33542207 | Inhibition of mPGES-1 attenuates efficient resolution of acute inflammation by enhancing CX3CL1 expression. | 2021 Feb 2 |
3 |
| 22 |
33568930 | Overview on the Discovery and Development of Anti-Inflammatory Drugs: Should the Focus Be on Synthesis or Degradation of PGE2? | 2021 |
2 |
| 23 |
33574423 | Clinical data mining reveals analgesic effects of lapatinib in cancer patients. | 2021 Feb 11 |
1 |
| 24 |
33582554 | Coordinated action of microsomal prostaglandin E synthase-1 and prostacyclin synthase on contact hypersensitivity. | 2021 Mar 26 |
3 |
| 25 |
33596205 | Robust COX-2-mediated prostaglandin response may drive arthralgia and bone destruction in patients with chronic inflammation post-chikungunya. | 2021 Feb |
1 |
| 26 |
33775835 | Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors. | 2021 Jun 1 |
3 |
| 27 |
33776573 | miR-708 Negatively Regulates TNFα/IL-1β Signaling by Suppressing NF-κB and Arachidonic Acid Pathways. | 2021 |
1 |
| 28 |
33788722 | Gene Deletion of Microsomal Prostaglandin E Synthase-1 Suppresses Chemically Induced Skin Carcinogenesis. | 2021 Mar |
1 |
| 29 |
33809724 | Effect of NIR Laser Therapy by MLS-MiS Source on Fibroblast Activation by Inflammatory Cytokines in Relation to Wound Healing. | 2021 Mar 16 |
1 |
| 30 |
33826984 | Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy. | 2021 Jul |
1 |
| 31 |
33930567 | Pathophysiological role of prostaglandin E synthases in liver diseases. | 2021 Jun |
1 |
| 32 |
34068550 | Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in Mice. | 2021 May 10 |
1 |
| 33 |
34084773 | Enhanced mPGES-1 Contributes to PD-Related Peritoneal Fibrosis via Activation of the NLRP3 Inflammasome. | 2021 |
3 |
| 34 |
34101620 | Sex-dependent compensatory mechanisms preserve blood pressure homeostasis in prostacyclin receptor-deficient mice. | 2021 Jul 15 |
1 |
| 35 |
34242345 | Sonlicromanol's active metabolite KH176m normalizes prostate cancer stem cell mPGES-1 overexpression and inhibits cancer spheroid growth. | 2021 |
4 |
| 36 |
34320346 | Prostaglandin E2 amplifies IL-17 production by γδ T cells during barrier inflammation. | 2021 Jul 27 |
1 |
| 37 |
34405222 | [Research advances of prostaglandin E2 synthases and receptors in cardiovascular diseases]. | 2021 Aug 25 |
2 |
| 38 |
35069250 | Low Salt Delivery Triggers Autocrine Release of Prostaglandin E2 From the Aldosterone-Sensitive Distal Nephron in Familial Hyperkalemic Hypertension Mice. | 2021 |
1 |
| 39 |
31536727 | Nardosinanone N suppresses LPS-induced macrophage activation by modulating the Nrf2 pathway and mPGES-1. | 2020 Mar |
1 |
| 40 |
31698145 | A review on mPGES-1 inhibitors: From preclinical studies to clinical applications. | 2020 Apr |
1 |
| 41 |
31732699 | EP2/4 Receptors Promote the Synthesis of PGE2 Increasing Tissue Damage in Bovine Endometrial Explants Induced by Escherichia coli. | 2020 Feb |
1 |
| 42 |
31868102 | Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis. | 2020 Apr |
2 |
| 43 |
32022480 | A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors. | 2020 Mar 18 |
1 |
| 44 |
32023904 | Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis. | 2020 Jan 31 |
1 |
| 45 |
32060421 | PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model. | 2020 Apr |
2 |
| 46 |
32094439 | A representative metalloprotease induces PGE2 synthesis in fibroblast-like synoviocytes via the NF-κB/COX-2 pathway with amplification by IL-1β and the EP4 receptor. | 2020 Feb 24 |
3 |
| 47 |
32155782 | Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells. | 2020 Mar 6 |
1 |
| 48 |
32231562 | Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells. | 2020 |
4 |
| 49 |
32251289 | mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway. | 2020 Apr 6 |
3 |
| 50 |
32295420 | Cardiovascular Biology of Prostanoids and Drug Discovery. | 2020 Jun |
1 |