Title : Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE2 biosynthesis by sonlicromanol's metabolite KH176m.

Pub. Date : 2021 Jan 13

PMID : 33441600






2 Functional Relationships(s)
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1 Finally, we showed that the effect of KH176m on mPGES-1 expression is due to the inhibition of a PGE2-driven positive feedback control-loop of mPGES-1 transcriptional regulation. Dinoprostone prostaglandin E synthase Mus musculus
2 Finally, we showed that the effect of KH176m on mPGES-1 expression is due to the inhibition of a PGE2-driven positive feedback control-loop of mPGES-1 transcriptional regulation. Dinoprostone prostaglandin E synthase Mus musculus