Title : Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.

Pub. Date : 2022 Jun 20

PMID : 35466565






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In our search for novel sEH inhibitors, we designed and synthesized novel analogs of the piperazine urea derivative 4, a previously discovered dual microsomal prostaglandin E2 synthase-1 (mPGES-1)/soluble epoxide hydrolase (sEH) inhibitor, to evaluate their potential as sEH inhibitors. Dinoprostone prostaglandin E synthase Mus musculus