Dexmedetomidine

toll-like receptor 4 ; Rattus norvegicus







37 Article(s)
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1 34878923 Protective effect of dexmedetomidine on intestinal mucosal barrier function in rats after cardiopulmonary bypass. 2022 Mar 3
2 35488217 Dexmedetomidine attenuates oxygen-glucose deprivation/ reperfusion-induced inflammation through the miR-17-5p/ TLR4/ NF-κB axis. 2022 Apr 29 3
3 35507967 Mechanism of dexmedetomidine preconditioning on spinal cord analgesia in rats with functional chronic visceral pain. 2022 1
4 33383282 Dexmedetomidine Resists Intestinal Ischemia-Reperfusion Injury by Inhibiting TLR4/MyD88/NF-κB Signaling. 2021 Apr 1
5 33639054 Dexmedetomidine Inhibits Inflammation to Alleviate Early Neuronal Injury via TLR4/NF-κB Pathway in Rats with Traumatic Brain Injury. 2021 1
6 34162568 Dexmedetomidine Attenuates Myocardial Injury Induced by Renal Ischemia/Reperfusion by Inhibiting the HMGB1-TLR4-MyD88-NF-κB Signaling Pathway. 2021 May 4
7 34509269 Protective role of dexmedetomidine against sevoflurane-induced postoperative cognitive dysfunction via the microRNA-129/TLR4 axis. 2021 Oct 2
8 34862872 Effects of dexmedetomidine on the degree of myocardial ischemia-reperfusion injury, oxidative stress and TLR4/NF-κB signaling pathway in rats. 2021 Sep 2
9 31912804 Dexmedetomidine Post-Conditioning Alleviates Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting High Mobility Group Protein B1 Group (HMGB1)/Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Signaling Pathway. 2020 Jan 8 4
10 32607919 Dexmedetomidine Alleviates CCI-Induced Neuropathic Pain via Inhibiting HMGB1-Mediated Astrocyte Activation and the TLR4/NF-κB Signaling Pathway in Rats. 2020 Oct 3
11 32706450 Analgesic effect of dexmedetomidine in rats after chronic constriction injury by mediating microRNA-101 expression and the E2F2-TLR4-NF-κB axis. 2020 Sep 5
12 31210339 Effect of dexmedetomidine on kidney injury in sepsis rats through TLR4/MyD88/NF-κB/iNOS signaling pathway. 2019 Jun 6
13 31373750 Dexmedetomidine protects against lung injury induced by limb ischemia-reperfusion via the TLR4/MyD88/NF-κB pathway. 2019 Nov 1
14 31520992 Dexmedetomidine-mediated protection against septic liver injury depends on TLR4/MyD88/NF-κB signaling downregulation partly via cholinergic anti-inflammatory mechanisms. 2019 Nov 4
15 31545263 Dexmedetomidine attenuates lipopolysaccharide induced acute lung injury in rats by inhibition of caveolin-1 downstream signaling. 2019 Oct 5
16 29241031 The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways. 2018 Feb 1
17 29510084 Dexmedetomidine reduces ventilator-induced lung injury (VILI) by inhibiting Toll-like receptor 4 (TLR4)/nuclear factor (NF)-κB signaling pathway. 2018 May 20 4
18 29842860 Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-κB pathway and the NLRP3 inflammasome may be involved in the mechanism. 2018 Nov 1 3
19 29926753 Dexmedetomidine attenuates cerebral ischemia/reperfusion injury in neonatal rats by inhibiting TLR4 signaling. 2018 Jul 4
20 27738803 Preventive effects of dexmedetomidine on the development of cognitive dysfunction following systemic inflammation in aged rats. 2017 Feb 1
21 27998004 Dexmedetomidine preconditioning for myocardial protection in ischaemia-reperfusion injury in rats by downregulation of the high mobility group box 1-toll-like receptor 4-nuclear factor κB signalling pathway. 2017 Mar 4
22 28000867 Dexmedetomidine may upregulate the expression of caveolin‑1 in lung tissues of rats with sepsis and improve the short‑term outcome. 2017 Feb 1
23 28222157 Dexmedetomidine preconditioning may attenuate myocardial ischemia/reperfusion injury by down-regulating the HMGB1-TLR4-MyD88-NF-кB signaling pathway. 2017 5
24 28302458 The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. 2017 Aug 2
25 28392361 Dexmedetomidine confers neuroprotection against transient global cerebral ischemia/reperfusion injury in rats by inhibiting inflammation through inactivation of the TLR-4/NF-κB pathway. 2017 May 10 3
26 28724211 Dexmedetomidine preconditioning protects against retinal ischemia/reperfusion injury and inhibits inflammation response via toll-like receptor 4 (TLR4) pathway. 2017 Sep 3
27 28753906 Dexmedetomidine preconditioning plays a neuroprotective role and suppresses TLR4/NF-κB pathways model of cerebral ischemia reperfusion. 2017 Sep 3
28 29201195 Anti-nociceptive effect of dexmedetomidine in a rat model of monoarthritis via suppression of the TLR4/NF-κB p65 pathway. 2017 Nov 3
29 29359143 Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling. 2017 4
30 27347929 Dexmedetomidine Protects Rat Liver against Ischemia-Reperfusion Injury Partly by the α2A-Adrenoceptor Subtype and the Mechanism Is Associated with the TLR4/NF-κB Pathway. 2016 Jun 23 3
31 29931961 [Dexmedetomidine prevents inflammatory responses in injured rat lung tissues induced by ischemia/reperfusion through inhibition of TLR4 expression]. 2016 Apr 8 8
32 25929655 The effect of dexmedetomidine on inflammatory response of septic rats. 2015 May 1 2
33 26070954 Dexmedetomidine ameliorates acute lung injury following orthotopic autologous liver transplantation in rats probably by inhibiting Toll-like receptor 4-nuclear factor kappa B signaling. 2015 Jun 13 3
34 26273145 Dexmedetomidine Ameliorate CLP-Induced Rat Intestinal Injury via Inhibition of Inflammation. 2015 2
35 26585410 Dexmedetomidine Inhibits TLR4/NF-κB Activation and Reduces Acute Kidney Injury after Orthotopic Autologous Liver Transplantation in Rats. 2015 Nov 20 3
36 24345905 Effect of dexmedetomidine on lung ischemia‑reperfusion injury. 2014 Feb 1
37 23690665 Dexmedetomidine inhibits inflammatory reaction in lung tissues of septic rats by suppressing TLR4/NF-κB pathway. 2013 3