Title : Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-κB pathway and the NLRP3 inflammasome may be involved in the mechanism.

Pub. Date : 2018 Nov 1

PMID : 29842860






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-kappaB pathway and the NLRP3 inflammasome may be involved in the mechanism. Dexmedetomidine toll-like receptor 4 Rattus norvegicus
2 Notably, DEX could also suppress the activation of the TLR4/NF-kappaB pathway and the NLRP3 inflammasome. Dexmedetomidine toll-like receptor 4 Rattus norvegicus
3 These findings suggested that treatment with DEX after SAH attenuated SAH-induced EBI, partially through the suppression of the TLR4/NF-kappaB pathway and the NLRP3 inflammasome. Dexmedetomidine toll-like receptor 4 Rattus norvegicus