Title : Dexmedetomidine ameliorates acute lung injury following orthotopic autologous liver transplantation in rats probably by inhibiting Toll-like receptor 4-nuclear factor kappa B signaling.

Pub. Date : 2015 Jun 13

PMID : 26070954






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Dexmedetomidine ameliorates acute lung injury following orthotopic autologous liver transplantation in rats probably by inhibiting Toll-like receptor 4-nuclear factor kappa B signaling. Dexmedetomidine toll-like receptor 4 Rattus norvegicus
2 Pretreatment with 50 mug/kg Dex attenuated OALT-induced lung injury in rats, probably by inhibiting the activation of the TLR4-NF-kappaB signaling pathway. Dexmedetomidine toll-like receptor 4 Rattus norvegicus
3 CONCLUSIONS: Dex exerts protective effects against ALI following OALT, and this protection is associated with the suppression of TLR4-NF-kappaB signaling. Dexmedetomidine toll-like receptor 4 Rattus norvegicus