| 1 |
35074429 | The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor. | 2022 Mar |
3 |
| 2 |
35166127 | d-Allulose Ameliorates Hyperglycemia Through IRE1α Sulfonation-RIDD-Sirt1 Decay Axis in the Skeletal Muscle. | 2022 Apr 18 |
2 |
| 3 |
35460012 | Berberine Improves TNF-α-Induced Hepatic Insulin Resistance by Targeting MEKK1/MEK Pathway. | 2022 Apr 22 |
2 |
| 4 |
35625712 | Incorporation of Oxidized Phenylalanine Derivatives into Insulin Signaling Relevant Proteins May Link Oxidative Stress to Signaling Conditions Underlying Chronic Insulin Resistance. | 2022 Apr 22 |
3 |
| 5 |
32798372 | Phosphorylated and O-GlcNAc Modified IRS-1 (Ser1101) and -2 (Ser1149) Contribute to Human Diabetes Type II. | 2021 |
1 |
| 6 |
33927970 | Role of insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in Alzheimer's disease. | 2021 Apr |
1 |
| 7 |
32337956 | Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation. | 2020 |
2 |
| 8 |
32383521 | Biotin, coenzyme Q10, and their combination ameliorate aluminium chloride-induced Alzheimer's disease via attenuating neuroinflammation and improving brain insulin signaling. | 2020 May 8 |
2 |
| 9 |
30640362 | Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease: A Secondary Analysis of the Exenatide-PD Trial. | 2019 Apr 1 |
2 |
| 10 |
30928401 | Didymin, a dietary citrus flavonoid exhibits anti-diabetic complications and promotes glucose uptake through the activation of PI3K/Akt signaling pathway in insulin-resistant HepG2 cells. | 2019 May 25 |
1 |
| 11 |
31539648 | Insulin and adipokine signaling and their cross-regulation in postmortem human brain. | 2019 Dec |
2 |
| 12 |
32010350 | ASSOCIATION OF IRS1 GLY971ARG GENE POLYMORPHISM WITH INSULIN RESISTANCE IN IRANIAN NEWLY DIAGNOSED DIABETIC ADULTS. | 2019 Jul-Sep |
2 |
| 13 |
32422022 | Hyperactivated Insulin Signaling Cascade in Human Glioblastoma Cells. | 2019 |
1 |
| 14 |
29233661 | Hypoglycemic mechanism of a novel proteoglycan, extracted from Ganoderma lucidum, in hepatocytes. | 2018 Feb 5 |
1 |
| 15 |
29393871 | Combination Treatment of Deep Sea Water and Fucoidan Attenuates High Glucose-Induced Insulin-Resistance in HepG2 Hepatocytes. | 2018 Feb 2 |
1 |
| 16 |
29526746 | Arsenic impairs insulin signaling in differentiated neuroblastoma SH-SY5Y cells. | 2018 May |
1 |
| 17 |
29679000 | Valsartan Alleviates Insulin Resistance in Skeletal Muscle of Chronic Renal Failure Rats. | 2018 Apr 21 |
1 |
| 18 |
29769704 | Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B. | 2018 Dec |
1 |
| 19 |
30052036 | Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β-Cell Destruction. | 2018 Aug 28 |
1 |
| 20 |
30092354 | Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3,4,5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain. | 2018 Nov |
2 |
| 21 |
30138966 | [Effect of AMPK/mTOR/S6K1 pathways and the insulin-sensitizing effect for adiponectin in endometrial cancer cells]. | 2018 Aug 25 |
1 |
| 22 |
30381640 | [Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction]. | 2018 |
2 |
| 23 |
28011403 | Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors. | 2017 Mar |
1 |
| 24 |
28082684 | Absence of IQGAP1 Protein Leads to Insulin Resistance. | 2017 Feb 24 |
2 |
| 25 |
28460125 | How Protein Kinase A Activates Canonical Tyrosine Kinase Signaling Pathways To Promote Granulosa Cell Differentiation. | 2017 Jul 1 |
1 |
| 26 |
28869341 | (-)-Epigallocatechin-3-gallate Ameliorates Insulin Resistance and Mitochondrial Dysfunction in HepG2 Cells: Involvement of Bmal1. | 2017 Dec |
1 |
| 27 |
29027136 | Oligonol promotes glucose uptake by modulating the insulin signaling pathway in insulin-resistant HepG2 cells via inhibiting protein tyrosine phosphatase 1B. | 2017 Nov |
1 |
| 28 |
26702053 | Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation. | 2016 Feb 26 |
3 |
| 29 |
26950447 | Differential actıvation and expression of insulin receptor substrate 1 (IRS1) in mononuclear cells of type 2 diabetes patients after insulin stimulation. | 2016 Feb 4 |
3 |
| 30 |
27434075 | High Glucose Impairs Insulin Signaling in the Glomerulus: An In Vitro and Ex Vivo Approach. | 2016 |
1 |
| 31 |
25445050 | Free fatty acid induced impairment of insulin signaling is prevented by the diastereomeric mixture of calophyllic acid and isocalophyllic acid in skeletal muscle cells. | 2015 Jan 5 |
1 |
| 32 |
25586176 | Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes. | 2015 Feb 27 |
2 |
| 33 |
25667086 | Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. | 2015 May |
5 |
| 34 |
25784556 | Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1. | 2015 Apr 24 |
2 |
| 35 |
25813876 | Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling. | 2015 Jul |
1 |
| 36 |
25815690 | Resveratrol analog piceatannol restores the palmitic acid-induced impairment of insulin signaling and production of endothelial nitric oxide via activation of anti-inflammatory and antioxidative heme oxygenase-1 in human endothelial cells. | 2015 Jul |
1 |
| 37 |
25875045 | Involvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells. | 2015 Jun |
1 |
| 38 |
25944785 | Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity. | 2015 Aug |
2 |
| 39 |
26108617 | Lipid-mediated muscle insulin resistance: different fat, different pathways? | 2015 Aug |
1 |
| 40 |
26143144 | Synergistic induction of insulin resistance by endothelin-1 and cAMP in 3T3-L1 adipocytes. | 2015 Oct |
4 |
| 41 |
26404168 | NOD2 activation induces oxidative stress contributing to mitochondrial dysfunction and insulin resistance in skeletal muscle cells. | 2015 Dec |
1 |
| 42 |
24068609 | Chronic insulin exposure does not cause insulin resistance but is associated with chemo-resistance in colon cancer cells. | 2014 Feb |
1 |
| 43 |
24337154 | A sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscle. | 2014 Mar |
2 |
| 44 |
24341419 | Trying to understand gestational diabetes. | 2014 Mar |
2 |
| 45 |
24652289 | Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation. | 2014 May 2 |
17 |
| 46 |
25120613 | Lopinavir inhibits insulin signaling by promoting protein tyrosine phosphatase 1B expression. | 2014 Sep |
2 |
| 47 |
25556062 | Modified Si-Miao-San inhibits inflammation and promotes glucose disposal in adipocytes through regulation of AMP-kinase. | 2014 Dec |
1 |
| 48 |
25580119 | Alternate Phosphorylation/O-GlcNAc Modification on Human Insulin IRSs: A Road towards Impaired Insulin Signaling in Alzheimer and Diabetes. | 2014 |
1 |
| 49 |
25606440 | IRS1 gene polymorphisms Gly972Arg and Ala513Pro are not associated with insulin resistance and type 2 diabetes risk in non-obese Turkish population. | 2014 Dec |
2 |
| 50 |
23174405 | Acute effects of different diet compositions on skeletal muscle insulin signalling in obese individuals during caloric restriction. | 2013 Apr |
2 |