| 1 |
34995924 | Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease. | 2022 Feb 5 |
1 |
| 2 |
32979285 | Phosphorylated full-length Tau interacts with 14-3-3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14-3-3 dimer. | 2021 Mar |
4 |
| 3 |
33380426 | Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation. | 2021 Jan-Jun |
1 |
| 4 |
33459229 | GSK-3 Inhibitors: A New Class of Drugs for Alzheimer's Disease Treatment. | 2021 |
1 |
| 5 |
33469985 | Protein kinase G phosphorylates the Alzheimer's disease-associated tau protein at distinct Ser/Thr sites. | 2021 Jan |
1 |
| 6 |
33652901 | Point Mutations of Nicotinic Receptor α1 Subunit Reveal New Molecular Features of G153S Slow-Channel Myasthenia. | 2021 Feb 26 |
1 |
| 7 |
34730359 | On the Microtubule-Stabilizing Properties of a Tau Oligopeptide. | 2021 Nov 22 |
1 |
| 8 |
34867294 | Simple, Single-Shot Phosphoproteomic Analysis of Heat-Stable Tau Identifies Age-Related Changes in pS235- and pS396-Tau Levels in Non-human Primates. | 2021 |
2 |
| 9 |
32067279 | Aβ monomer induces phosphorylation of Tau at Ser-214 through β2AR-PKA-JNK signaling pathway. | 2020 Apr |
2 |
| 10 |
32300132 | Oligomeric amyloid-β induces early and widespread changes to the proteome in human iPSC-derived neurons. | 2020 Apr 16 |
1 |
| 11 |
33110983 | Machine Learning for Discovery of GSK3β Inhibitors. | 2020 Oct 20 |
2 |
| 12 |
30342424 | Tau Tubulin Kinase 1 (TTBK1), a new player in the fight against neurodegenerative diseases. | 2019 Jan 1 |
1 |
| 13 |
30423399 | Phosphorylation of serine 305 in tau inhibits aggregation. | 2019 Jan 23 |
1 |
| 14 |
30767766 | A walk through tau therapeutic strategies. | 2019 Feb 15 |
2 |
| 15 |
30893872 | Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer's Disease. | 2019 Mar 19 |
3 |
| 16 |
30958368 | Phospho-Tau Changes in the Human CA1 During Alzheimer's Disease Progression. | 2019 |
3 |
| 17 |
30985105 | O-GlcNAc Modification Protects against Protein Misfolding and Aggregation in Neurodegenerative Disease. | 2019 May 15 |
1 |
| 18 |
31131395 | Increased Tau Phosphorylation in Motor Neurons From Clinically Pure Sporadic Amyotrophic Lateral Sclerosis Patients. | 2019 Jul 1 |
1 |
| 19 |
31504677 | Tau Phosphorylation and Aggregation in the Developing Human Brain. | 2019 Oct 1 |
2 |
| 20 |
31864418 | Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology. | 2019 Dec 21 |
1 |
| 21 |
32096026 | Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications. | 2019 |
1 |
| 22 |
29127203 | Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment. | 2018 Jan 5 |
1 |
| 23 |
29332046 | A Novel Antibody Targeting Tau Phosphorylated at Serine 235 Detects Neurofibrillary Tangles. | 2018 |
2 |
| 24 |
27989667 | Ser422 phosphorylation blocks human Tau cleavage by caspase-3: Biochemical implications to Alzheimer's Disease. | 2017 Feb 1 |
2 |
| 25 |
27998769 | Passive immunization targeting the N-terminal region of phosphorylated tau (residues 68-71) improves spatial memory in okadaic acid induced tauopathy model rats. | 2017 Jan 29 |
1 |
| 26 |
28328017 | Dental pulp stem cells promote regeneration of damaged neuron cells on the cellular model of Alzheimer's disease. | 2017 Jun |
1 |
| 27 |
28416463 | Glucocorticoids activate a synapse weakening pathway culminating in tau phosphorylation in the hippocampus. | 2017 Jul |
1 |
| 28 |
28435263 | Neuroprotection against apoptosis of SK-N-MC cells using RMP-7- and lactoferrin-grafted liposomes carrying quercetin. | 2017 |
1 |
| 29 |
28521765 | Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice. | 2017 May 18 |
1 |
| 30 |
28760828 | An acetylation-phosphorylation switch that regulates tau aggregation propensity and function. | 2017 Sep 15 |
4 |
| 31 |
29215007 | Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau. | 2017 Dec 7 |
1 |
| 32 |
25465240 | Olfactory Deprivation Hastens Alzheimer-Like Pathologies in a Human Tau-Overexpressed Mouse Model via Activation of cdk5. | 2016 Jan |
2 |
| 33 |
26582459 | S6 kinase phosphorylated at T229 is involved in tau and actin pathologies in Alzheimer's disease. | 2016 Aug |
1 |
| 34 |
26629858 | Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies. | 2016 Jan 27 |
1 |
| 35 |
26671985 | Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy. | 2016 Jan |
1 |
| 36 |
27073990 | DYRK1A inhibition as potential treatment for Alzheimer's disease. | 2016 Apr |
1 |
| 37 |
27128182 | Potent anticholinesterasic and neuroprotective pyranotacrines as inhibitors of beta-amyloid aggregation, oxidative stress and tau-phosphorylation for Alzheimer's disease. | 2016 Aug 8 |
1 |
| 38 |
27280380 | Gramine Derivatives Targeting Ca(2+) Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases. | 2016 Jul 14 |
1 |
| 39 |
27373205 | Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport. | 2016 Sep |
1 |
| 40 |
25041093 | Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice. | 2015 Jan |
2 |
| 41 |
25524708 | Temporally distinct phosphorylations differentiate Tau-dependent learning deficits and premature mortality in Drosophila. | 2015 Apr 1 |
4 |
| 42 |
25878277 | Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy. | 2015 Apr 15 |
1 |
| 43 |
25899925 | Parkinson's disease-associated PINK1 G309D mutation increases abnormal phosphorylation of Tau. | 2015 Apr |
1 |
| 44 |
25914109 | Effects of antibodies to phosphorylated and non-phosphorylated tau on in vitro tau phosphorylation at Serine-199: Preliminary report. | 2015 Jul |
2 |
| 45 |
26238538 | Innovative Anthocyanin/Anthocyanidin Formulation Protects SK-N-SH Cells Against the Amyloid-β Peptide-Induced Toxicity: Relevance to Alzheimer's Disease. | 2015 |
1 |
| 46 |
26330100 | ELISA measurement of specific antibodies to phosphorylated tau in intravenous immunoglobulin products. | 2015 Oct |
2 |
| 47 |
24033439 | Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. | 2014 Feb |
4 |
| 48 |
24444746 | O-GlcNAc modification of tau directly inhibits its aggregation without perturbing the conformational properties of tau monomers. | 2014 Apr 17 |
1 |
| 49 |
24603903 | microRNA-9 attenuates amyloidβ-induced synaptotoxicity by targeting calcium/calmodulin-dependent protein kinase kinase 2. | 2014 May |
1 |
| 50 |
22710920 | Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration. | 2013 |
1 |