Title : Gramine Derivatives Targeting Ca(2+) Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases.

Pub. Date : 2016 Jul 14

PMID : 27280380






1 Functional Relationships(s)
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1 Furthermore, we hypothesize that these compounds decrease tau hyperphosphorylation based on the maintenance of the Ser/Thr phosphatase activity and their neuroprotection against the damage caused by okadaic acid. Serine microtubule associated protein tau Homo sapiens