Title : DYRK1A inhibition as potential treatment for Alzheimer's disease.

Pub. Date : 2016 Apr

PMID : 27073990






1 Functional Relationships(s)
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1 DYRK1A phosphorylates tau on 11 different Ser/Thr residues, resulting in the formation of aggregates called "neurofibrillary tangles" which, together with amyloid plaques, could be responsible for dementia, neuronal degeneration and cell death. Serine microtubule associated protein tau Homo sapiens