Title : Hypoxia/reoxygenation induces apoptosis through a ROS-mediated caspase-8/Bid/Bax pathway in human lymphocytes.

Pub. Date : 2007 Nov 23

PMID : 17904098






1 Functional Relationships(s)
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1 N-acetylcysteine (NAC), a well-known ROS scavenger, suppressed caspase-8 activation and the subsequent cleavage of caspase-9 and caspase-3, indicating the role of ROS in caspase-8-mediated apoptosis. Reactive Oxygen Species caspase 9 Homo sapiens