Title : Reactive oxygen species and p38 mitogen-activated protein kinase induce apoptotic death of U937 cells in response to Naja nigricollis toxin-gamma.

Pub. Date : 2009 Aug

PMID : 20187293






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Taken together, these results suggest that the cytotoxicity of toxin- is initiated by p38-MAPK-mediated mitochondrial dysfunction followed by ROS production and activation of caspases, and that ROS further augments p38 MAPK activation and mitochondrial alteration. Reactive Oxygen Species caspase 9 Homo sapiens