Title : Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.

Pub. Date : 2005 Aug 15

PMID : 16103097






1 Functional Relationships(s)
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1 Data suggest that in the presence of mitochondrial-derived ROS, TRAIL induced mitochondrial release of Smac/DIABLO and inactivation of X-linked inhibitor of apoptosis through caspase-9-independent activation of caspase 3. Reactive Oxygen Species caspase 9 Homo sapiens