7,8-dihydro-8-oxoguanine

8-oxoguanine DNA glycosylase ; Homo sapiens







49 Article(s)
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1 33855116 Real-time Base Excision Repair Assay to Measure the Activity of the 8-oxoguanine DNA Glycosylase 1 in Isolated Mitochondria of Human Skin Fibroblasts. 2021 Mar 20 4
2 33925271 NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487. 2021 Apr 27 4
3 34093997 Recognition of a tandem lesion by DNA bacterial formamidopyrimidine glycosylases explored combining molecular dynamics and machine learning. 2021 2
4 34948899 Determination of Novel Anti-Cancer Agents by Targeting OGG1 Enzyme Using Integrated Bioinformatics Methods. 2021 Dec 16 4
5 33114607 OGG1 Inhibitor TH5487 Alters OGG1 Chromatin Dynamics and Prevents Incisions. 2020 Oct 26 4
6 31408726 Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation. 2019 Nov 1 1
7 31652414 Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid. 2019 Dec 5
8 29320630 Structural Insight into the Discrimination between 8-Oxoguanine Glycosidic Conformers by DNA Repair Enzymes: A Molecular Dynamics Study of Human Oxoguanine Glycosylase 1 and Formamidopyrimidine-DNA Glycosylase. 2018 Feb 20 3
9 25660075 Acetylated 8-oxoguanine DNA glycosylase 1 and its relationship with p300 and SIRT1 in lens epithelium cells from age-related cataract. 2015 Jun 4
10 26187872 Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling. 2015 Dec 6
11 26221032 CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage. 2015 Sep 11 2
12 24430338 Oxidative stress is responsible for genotoxicity of camphorquinone in primary human gingival fibroblasts. 2014 Jul 1
13 24589083 Expression of 8-oxoguanine glycosylase in human fetal membranes. 2014 Jul 1
14 23868064 Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress. 2013 Jul 18 4
15 22829015 Novel mutations of OGG1 base excision repair pathway gene in laryngeal cancer patients. 2012 Dec 2
16 22989888 DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase. 2012 Oct 26 4
17 21195604 First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes. 2011 May 4
18 21343179 Thermodynamic and kinetic basis for recognition and repair of 8-oxoguanine in DNA by human 8-oxoguanine-DNA glycosylase. 2011 Jun 2
19 22320992 OGG1 gene sequence variation in head and neck cancer patients in Pakistan. 2011 1
20 19527055 Structure-dependent DNA damage and repair in a trinucleotide repeat sequence. 2009 Jul 21 3
21 19615952 Repair activities of human 8-oxoguanine DNA glycosylase are stimulated by the interaction with human checkpoint sensor Rad9-Rad1-Hus1 complex. 2009 Oct 2 4
22 19647792 Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells. 2009 Oct 15 1
23 18672903 Correlated cleavage of damaged DNA by bacterial and human 8-oxoguanine-DNA glycosylases. 2008 Aug 26 2
24 17127104 Oxidative damage to purines in DNA: role of mammalian Ogg1. 2007 Apr 1 1
25 17197252 Is the repair of oxidative DNA base modifications inducible by a preceding DNA damage induction? 2007 Mar 1 2
26 17951408 Human 8-oxoguanine DNA glycosylase suppresses the oxidative stress induced apoptosis through a p53-mediated signaling pathway in human fibroblasts. 2007 Oct 2
27 16472828 Exogenous 8-oxo-dG is not utilized for nucleotide synthesis but enhances the accumulation of 8-oxo-Gua in DNA through error-prone DNA synthesis. 2006 Apr 11 1
28 16478987 Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo. 2006 Mar 4
29 16737853 The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change. 2006 Jul 13 1
30 16928690 High resolution characterization of formamidopyrimidine-DNA glycosylase interaction with its substrate by chemical cross-linking and mass spectrometry using substrate analogs. 2006 Oct 27 4
31 15723719 Lung cancer in smoking patients inversely alters the activity of hOGG1 and hNTH1. 2005 Mar 10 1
32 14742311 Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo. 2004 Jun 2
33 15350146 Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases. 2004 Sep 14 4
34 15554188 [New non-hydrolyzable substrate analogs for 8-oxoguanine-DNA glycosylases]. 2004 Sep-Oct 2
35 12692799 8-oxoguanine lesioned B-DNA molecule complexed with repair enzyme hOGG1: a molecular dynamics study. 2003 May 1
36 12960370 Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases. 2003 Sep 16 2
37 14642563 Immunofluorescent localization of the murine 8-oxoguanine DNA glycosylase (mOGG1) in cells growing under normal and nutrient deprivation conditions. 2003 Dec 9 1
38 11927502 Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. 2002 Apr 1
39 12000832 Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. 2002 May 15 2
40 12034821 Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo. 2002 Jun 1 1
41 12447686 A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage. 2002 Nov 28 2
42 11139613 Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair. 2001 Jan 15 6
43 11459633 DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326. 2001 Aug 9 4
44 11554298 DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes. 2001 1
45 12903244 Enzymatic properties of Escherichia coli and human 7,8-dihydro-8-oxoguanine DNA glycosylases. 2000 1
46 10469635 Overexpression of Ogg1 in mammalian cells: effects on induced and spontaneous oxidative DNA damage and mutagenesis. 1999 Sep 2
47 9611236 Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage. 1998 Jun 15 2
48 9662341 Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours. 1998 Jun 11 1
49 9372850 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity. 1997 Oct 3