Title : Correlated cleavage of damaged DNA by bacterial and human 8-oxoguanine-DNA glycosylases.

Pub. Date : 2008 Aug 26

PMID : 18672903






2 Functional Relationships(s)
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1 We have used a recently developed correlated cleavage assay to investigate whether this mechanism operates for Fpg and OGG1, two structurally unrelated DNA glycosylases that excise an important oxidative lesion, 7,8-dihydro-8-oxoguanine (8-oxoG), from DNA. 7,8-dihydro-8-oxoguanine 8-oxoguanine DNA glycosylase Homo sapiens
2 We have used a recently developed correlated cleavage assay to investigate whether this mechanism operates for Fpg and OGG1, two structurally unrelated DNA glycosylases that excise an important oxidative lesion, 7,8-dihydro-8-oxoguanine (8-oxoG), from DNA. 7,8-dihydro-8-oxoguanine 8-oxoguanine DNA glycosylase Homo sapiens