Title : 8-oxoguanine lesioned B-DNA molecule complexed with repair enzyme hOGG1: a molecular dynamics study.

Pub. Date : 2003 May

PMID : 12692799






1 Functional Relationships(s)
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1 The molecular dynamics (MD) simulation of DNA mutagenic oxidative lesion, 7,8-dihydro-8-oxoguanine (8-oxoG), complexed with the repair enzyme, human oxoguanine glycosylase 1 (hOGG1), was performed for 1 nanosecond (ns) in order to describe the dynamical process of DNA-enzyme complex formation. 7,8-dihydro-8-oxoguanine 8-oxoguanine DNA glycosylase Homo sapiens