Title : Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells.

Pub. Date : 2009 Oct 15

PMID : 19647792






1 Functional Relationships(s)
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1 The MQ-induced dose-dependent increase in mtDNA damage was attenuated by overexpressing mitochondrial 8-oxoguanine DNA glycosylase (Ogg1), consistent with 7,8-dihydro-8-oxoguanine being a major oxidative mtDNA lesion. 7,8-dihydro-8-oxoguanine 8-oxoguanine DNA glycosylase Homo sapiens