phosphatidylinositol 3,4,5-triphosphate

phosphatase and tensin homolog ; Mus musculus







32 Article(s)
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Pub. Year
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1 31570383 PTEN Mouse Models of Cancer Initiation and Progression. 2020 Feb 3 1
2 33065020 Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression. 2020 Oct 15 1
3 33276499 PTEN and Other PtdIns(3,4,5)P3 Lipid Phosphatases in Breast Cancer. 2020 Dec 2 1
4 25520316 Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN. 2015 Jan 1
5 24392697 Turning off AKT: PHLPP as a drug target. 2014 1
6 24658595 Role of aberrant PI3K pathway activation in gallbladder tumorigenesis. 2014 Feb 28 1
7 24766807 Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function. 2014 Apr 24 1
8 24805236 PTEN action in leukaemia dictated by the tissue microenvironment. 2014 Jun 19 1
9 24048858 DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination. 2013 Sep 18 1
10 22150431 Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor. 2012 Feb 15 1
11 21521784 Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model. 2011 Jun 16 1
12 21531890 Protein kinase CK2/PTEN pathway plays a key role in platelet-activating factor-mediated murine anaphylactic shock. 2011 Jun 1 1
13 21926349 PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability. 2011 Nov 17 1
14 19286998 Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia. 2009 May 14 1
15 19875726 Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness. 2009 Dec 4 1
16 18178811 The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells. 2008 Jan 15 1
17 18201277 Portrait of PTEN: messages from mutant mice. 2008 Feb 1
18 18339867 The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration. 2008 Mar 15 1
19 18794881 Understanding PTEN regulation: PIP2, polarity and protein stability. 2008 Sep 18 1
20 17195063 Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity. 2007 Feb 1
21 17341655 PTEN, more than the AKT pathway. 2007 Jul 1
22 17371230 Role of PTEN/PI3K pathway in endothelial cells. 2007 Apr 1
23 16880400 Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN. 2006 Aug 8 1
24 16214396 Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma. 2005 Oct 1
25 15289934 Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrane fraction. 2004 Aug 3
26 15467489 The role of PTEN in allergic inflammation. 2004 Jul-Aug 1
27 12563260 Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. 2003 Mar 1
28 12671058 Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. 2003 Apr 1
29 11916922 Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice. 2002 Apr 2
30 12163562 CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. 2002 Aug 5 1
31 10339565 PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. 1999 May 25 3
32 9778245 Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. 1998 Oct 2 1