Title : Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia.

Pub. Date : 2009 May 14

PMID : 19286998






1 Functional Relationships(s)
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1 Phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) signaling in neutrophils was elevated by depleting PTEN, a phosphatidylinositol 3"-phosphatase that hydrolyzes PtdIns(3,4,5)P(3). phosphatidylinositol 3,4,5-triphosphate phosphatase and tensin homolog Mus musculus