| 1 |
35264157 | Novel sequential therapy with metformin enhances the effects of cisplatin in testicular germ cell tumours via YAP1 signalling. | 2022 Mar 9 |
1 |
| 2 |
33268288 | Metformin decreased myocardial fibrosis and apoptosis in hyperhomocysteinemia -induced cardiac hypertrophy. | 2021 Jan |
1 |
| 3 |
33562646 | Metformin and Androgen Receptor-Axis-Targeted (ARAT) Agents Induce Two PARP-1-Dependent Cell Death Pathways in Androgen-Sensitive Human Prostate Cancer Cells. | 2021 Feb 5 |
1 |
| 4 |
33758522 | Gene Expression Profiling of Apoptotic Proteins in Circulating Peripheral Blood Mononuclear Cells in Type II Diabetes Mellitus and Modulation by Metformin. | 2021 |
1 |
| 5 |
33886150 | Pitavastatin and metformin synergistically activate apoptosis and autophagy in pancreatic cancer cells. | 2021 Aug |
1 |
| 6 |
34078517 | Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism. | 2021 Jun 1 |
3 |
| 7 |
31786336 | Protective effect of metformin against palmitate-induced hepatic cell death. | 2020 Mar 1 |
1 |
| 8 |
31894313 | Metformin alleviates endometrial hyperplasia through the UCA1/miR‑144/TGF‑β1/AKT signaling pathway. | 2020 Feb |
2 |
| 9 |
32023702 | [Effect of metformin on mitochondrial pathway of apoptosis and oxidative stress in cell model of nonalcoholic fatty liver disease]. | 2020 Jan 20 |
1 |
| 10 |
32495867 | Metformin reduces pancreatic cancer cell proliferation and increases apoptosis through MTOR signaling pathway and its dose-effect relationship. | 2020 May |
1 |
| 11 |
30625181 | Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells. | 2019 |
1 |
| 12 |
30664988 | The effect of metformin on biomarkers and survivals for breast cancer- a systematic review and meta-analysis of randomized clinical trials. | 2019 Mar |
1 |
| 13 |
30720062 | Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. | 2019 Apr |
2 |
| 14 |
31014052 | [The mechanism of aspirin combined with metformin induced apoptosis of thyroid cancer TPC-1 cells]. | 2019 Apr 23 |
1 |
| 15 |
31173255 | Effect of metformin on cell proliferation, apoptosis, migration and invasion in A172 glioma cells and its mechanisms. | 2019 Aug |
1 |
| 16 |
29117515 | Metformin and epothilone A treatment up regulate pro-apoptotic PARP-1, Casp-3 and H2AX genes and decrease of AKT kinase level to control cell death of human hepatocellular carcinoma and ovary adenocarcinoma cells. | 2018 Mar |
2 |
| 17 |
29385181 | Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy. | 2018 |
1 |
| 18 |
30032136 | Metformin and FTY720 Synergistically Induce Apoptosis in Multiple Myeloma Cells. | 2018 |
1 |
| 19 |
30266241 | Efficacy of metformin in mediating cellular uptake and inducing apoptosis activity of doxorubicin. | 2018 Nov |
1 |
| 20 |
30481793 | Metformin Inhibited Growth, Invasion and Metastasis of Esophageal Squamous Cell Carcinoma in Vitro and in Vivo. | 2018 |
1 |
| 21 |
28391030 | Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients. | 2017 May |
1 |
| 22 |
29344202 | Metformin in combination with cisplatin inhibits cell viability and induces apoptosis of human ovarian cancer cells by inactivating ERK 1/2. | 2017 Dec |
1 |
| 23 |
26876755 | Metformin prevents cerebellar granule neurons against glutamate-induced neurotoxicity. | 2016 Mar |
1 |
| 24 |
27391065 | Metformin as a new anti-cancer drug in adrenocortical carcinoma. | 2016 Aug 2 |
1 |
| 25 |
27474170 | Metformin increases PDH and suppresses HIF-1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma. | 2016 Aug 23 |
2 |
| 26 |
27779693 | Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo. | 2016 Dec |
1 |
| 27 |
25305450 | Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models. | 2015 Jan 28 |
1 |
| 28 |
26056043 | Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2. | 2015 Aug 28 |
1 |
| 29 |
26111693 | [Effects of metformin on apoptosis induced by advanced glycation end-products and expressions of caspase-3, Bax and Bcl-2 in human dermal fibroblasts in vitro]. | 2015 Jun |
1 |
| 30 |
26117007 | [Effect of Metformin on Proliferation, Differentiation and Apoptosis of THP-1 Cells]. | 2015 Jun |
1 |
| 31 |
24297263 | Protective effect of metformin against cisplatin-induced ototoxicity in an auditory cell line. | 2014 Apr |
1 |
| 32 |
24589588 | [Effects of metformin on human oral cancer KB cell proliferation and apoptosis in vitro]. | 2014 Feb |
1 |
| 33 |
24940426 | Effect of metformin on the human T98G glioblastoma multiforme cell line. | 2014 May |
1 |
| 34 |
24966801 | Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis. | 2014 |
1 |
| 35 |
24969550 | Metformin mitigates apoptosis in ischemic myocardium. | 2014 Nov |
3 |
| 36 |
22436702 | Effects of some anti-diabetic and cardioprotective agents on proliferation and apoptosis of human coronary artery endothelial cells. | 2012 Mar 21 |
1 |
| 37 |
22524458 | In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma. | 2012 Sep |
1 |
| 38 |
22575507 | Metformin induces differentiation in acute promyelocytic leukemia by activating the MEK/ERK signaling pathway. | 2012 Jun 8 |
1 |
| 39 |
21388661 | Induction of apoptosis by metformin in epithelial ovarian cancer: involvement of the Bcl-2 family proteins. | 2011 Jun 1 |
2 |
| 40 |
21979311 | Protective role of antidiabetic drug metformin against gentamicin induced apoptosis in auditory cell line. | 2011 Dec |
1 |
| 41 |
20038265 | Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells. | 2010 Jun |
1 |
| 42 |
20215500 | Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells. | 2010 Mar 15 |
1 |
| 43 |
19084933 | Metformin induces apoptosis of pancreatic cancer cells. | 2008 Dec 21 |
1 |
| 44 |
16868748 | Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3. | 2006 Sep |
3 |