Title : Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.

Pub. Date : 2015 Aug 28

PMID : 26056043






1 Functional Relationships(s)
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1 Metformin combined with aspirin significantly inhibited the phosphorylation of mTOR and STAT3, and induced apoptosis as measured by caspase-3 and PARP cleavage. Metformin caspase 3 Homo sapiens