Title : Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients.

Pub. Date : 2017 May

PMID : 28391030






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 EGFR downstream signaling evaluation further demonstrated that metformin, at its IC50 value, modified apoptosis caused in erlotinib or chemotherapeutic agent-treated cells via AKT activation and the inhibition of caspase 3 and PARP cleavages. Metformin caspase 3 Homo sapiens