Doxorubicin

caspase 3 ; Homo sapiens







224 Article(s)
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101 25561091 Cytotoxicity and induction of apoptosis by formamidinodoxorubicins in comparison to doxorubicin in human ovarian adenocarcinoma cells. 2015 Jan 1
102 25566959 Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation. 2015 May 1
103 25605018 Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance. 2015 Feb 20 1
104 25658463 WIP1 phosphatase as a potential therapeutic target in neuroblastoma. 2015 1
105 25760224 Inhibition of Forkhead box protein M1 by thiostrepton increases chemosensitivity to doxorubicin in T-cell acute lymphoblastic leukemia. 2015 Jul 1
106 25775367 Polymeric nanomedicine for tumor-targeted combination therapy to elicit synergistic genotoxicity against prostate cancer. 2015 Apr 1 1
107 25895636 Oscillation of apoptosome formation through assembly of truncated Apaf-1. 2015 Aug 5 1
108 25997894 Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts. 2015 Aug 6 1
109 26137410 Immune independent crosstalk between lymphoma and myeloid suppressor CD14+HLA-DRlow/neg monocytes mediates chemotherapy resistance. 2015 Apr 1
110 26252906 Phenethyl isothiocyanate enhances adriamycin‑induced apoptosis in osteosarcoma cells. 2015 Oct 1
111 26261798 Elevation of cAMP Levels Inhibits Doxorubicin-Induced Apoptosis in Pre- B ALL NALM- 6 Cells Through Induction of BAD Phosphorylation and Inhibition of P53 Accumulation. 2015 Spring 1
112 26263187 Optimization of a Stable Linker Involved DEVD Peptide-Doxorubicin Conjugate That Is Activated upon Radiation-Induced Caspase-3-Mediated Apoptosis. 2015 Aug 27 2
113 26340617 Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells. 2015 Sep 1 1
114 26548747 Phenethyl isothiocyanate potentiates anti-tumour effect of doxorubicin through Akt-dependent pathway. 2015 Dec 1
115 26645568 Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells. 2015 1
116 26770398 The survivin suppressant YM155 reverses doxorubicin resistance in osteosarcoma. 2015 3
117 23956031 Folate decorated magnetite nanoparticles: synthesis and targeted therapy against ovarian cancer. 2014 Feb 1
118 24239681 Luminescent mesoporous nanoreservoirs for the effective loading and intracellular delivery of therapeutic drugs. 2014 Mar 4
119 24525822 Transactivation of bad by vorinostat-induced acetylated p53 enhances doxorubicin-induced cytotoxicity in cervical cancer cells. 2014 Feb 14 1
120 24998637 Induction of apoptosis by doxorubicin-transferrin conjugate compared to free doxorubicin in the human leukemia cell lines. 2014 Sep 5 1
121 25294909 Doxorubicin synergizes with 34.5ENVE to enhance antitumor efficacy against metastatic ovarian cancer. 2014 Dec 15 1
122 26351207 Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway. 2014 1
123 22674530 Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway. 2013 Jan 1
124 23200181 The Combined effects of hematoporphyrin monomethyl ether-SDT and doxorubicin on the proliferation of QBC939 cell lines. 2013 Jan 1
125 23647679 Retaining cytotoxic activity of anthrapyridone CO1 against multidrug resistant cells is related to the ability to induce concomitantly apoptosis and lysosomal death of leukaemia HL60/VINC and HL60/DOX cells. 2013 Jun 1
126 23818927 Decursin and Doxorubicin Are in Synergy for the Induction of Apoptosis via STAT3 and/or mTOR Pathways in Human Multiple Myeloma Cells. 2013 1
127 23881906 Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-triggered nanoaggregation probe. 2013 Sep 27 2
128 23965518 The sulphydryl containing ACE inhibitor Zofenoprilat protects coronary endothelium from Doxorubicin-induced apoptosis. 2013 Oct 1
129 24021537 Didox potentiates the cytotoxic profile of doxorubicin and protects from its cardiotoxicity. 2013 Oct 15 1
130 24064045 Doxorubicin induces cell death in breast cancer cells regardless of Survivin and XIAP expression levels. 2013 Aug-Sep 1
131 21940668 Doxorubicin acts via mitochondrial ROS to stimulate catabolism in C2C12 myotubes. 2012 Jan 1 1
132 21947872 NAD(P)H:quinone oxidoreductase 1 is induced by progesterone in cardiomyocytes. 2012 Jun 1
133 22198116 Anthraquinone antitumour agents, doxorubicin, pirarubicin and benzoperimidine BP1, trigger caspase-3/caspase-8-dependent apoptosis of leukaemia sensitive HL60 and resistant HL60/VINC and HL60/DOX cells. 2012 Apr 2
134 22305266 Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line. 2012 Feb 4 2
135 22323498 Regulation of interferon-inducible proteins by doxorubicin via interferon Îł-Janus tyrosine kinase-signal transducer and activator of transcription signaling in tumor cells. 2012 May 1
136 22375097 Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation. 2012 1
137 22569233 Beneficial effects of curcumin on antitumor activity and adverse reactions of doxorubicin. 2012 Aug 1 1
138 22581584 ADAM10 overexpression confers resistance to doxorubicin-induced apoptosis in hepatocellular carcinoma. 2012 Oct 1
139 22770903 Design and development of a whole-cell luminescent biosensor for detection of early-stage of apoptosis. 2012 Oct-Dec 1
140 22781804 [Experimental study of up-regulating PTEN gene on increasing the chemosensitivity in K562/ADM cells]. 2012 May 1
141 22895638 Hollow superparamagnetic iron oxide nanoshells as a hydrophobic anticancer drug carrier: intracelluar pH-dependent drug release and enhanced cytotoxicity. 2012 Sep 21 1
142 23028696 Probing the dynamics of doxorubicin-DNA intercalation during the initial activation of apoptosis by fluorescence lifetime imaging microscopy (FLIM). 2012 1
143 20461381 Histone deacetylase inhibitor (HDACI) PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells. 2011 Feb 1
144 21818667 Comparative cellular and molecular analysis of cytotoxicity and apoptosis induction by doxorubicin and Baneh in human breast cancer T47D cells. 2011 Oct 1
145 21865289 Doxorubicin-induced platelet procoagulant activities: an important clue for chemotherapy-associated thrombosis. 2011 Nov 1
146 20405239 Protective effect of PACAP against doxorubicin-induced cell death in cardiomyocyte culture. 2010 Nov 1
147 20508289 Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells. 2010 Mar-Apr 1
148 20512627 N,N-Dimethyl phytosphingosine sensitizes HL-60/MX2, a multidrug-resistant variant of HL-60 cells, to doxorubicin-induced cytotoxicity through ROS-mediated release of cytochrome c and AIF. 2010 Aug 3
149 20528452 Enhanced binding and killing of target tumor cells by drug-loaded liposomes modified with tumor-specific phage fusion coat protein. 2010 Jun 2
150 20663232 TRAIL sensitize MDR cells to MDR-related drugs by down-regulation of P-glycoprotein through inhibition of DNA-PKcs/Akt/GSK-3beta pathway and activation of caspases. 2010 Jul 28 1