Doxorubicin

caspase 3 ; Homo sapiens







224 Article(s)
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151 20682173 Sensitization of osteosarcoma cell line SaOS-2 to chemotherapy by downregulating survivin. 2010 Apr 1
152 20884855 Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. 2010 Oct 19 1
153 21078300 PIH1D1, a subunit of R2TP complex, inhibits doxorubicin-induced apoptosis. 2010 Dec 17 1
154 21364639 The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity. 2010 1
155 19082486 Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines. 2009 Jan 1
156 19190340 Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy. 2009 Feb 15 1
157 19426282 Doxorubicin-induced platelet cytotoxicity: a new contributory factor for doxorubicin-mediated thrombocytopenia. 2009 Jul 2
158 19902123 Evaluating the antitumor activity of combined photochemotherapy mediated by a meso-substituted tetracationic porphyrin and adriamycin. 2009 Nov 1
159 20193325 [Apoptosis in Jurkat cells induced by bortezomib combined with adriamycin]. 2009 Dec 1
160 17935137 Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death. 2008 Jan 15 1
161 17996985 The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells. 2008 Mar-Apr 1
162 18164246 The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2. 2008 Jan 1
163 18278454 Down-regulation of tissue factor by siRNA increased doxorubicin-induced apoptosis in human neuroblastoma. 2008 Feb 1
164 18422996 Abundant anti-apoptotic BCL-2 is a molecular target in leukaemias with t(4;11) translocation. 2008 Jun 1
165 18758960 Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3. 2008 Oct 2
166 18852119 Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway. 2008 Oct 1
167 16937080 The anti-hepatitis drug DDB chemosensitizes multidrug resistant cancer cells in vitro and in vivo by inhibiting P-gp and enhancing apoptosis. 2007 Apr 1
168 17097318 siRNA-mediated type 1 insulin-like growth factor receptor silencing induces chemosensitization of a human liver cancer cell line with mutant P53. 2007 Feb 1
169 17542780 Morphine inhibits doxorubicin-induced reactive oxygen species generation and nuclear factor kappaB transcriptional activation in neuroblastoma SH-SY5Y cells. 2007 Sep 1 1
170 17706502 Novel action of epidermal growth factor on caspase 3 and its potential as a chemotherapeutic adjunct for neuroblastoma. 2007 Aug 2
171 17922852 Low concentrations of doxorubicin sensitizes human solid cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-receptor (R) 2-mediated apoptosis by inducing TRAIL-R2 expression. 2007 Dec 1
172 17959036 Interferon-alpha enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin by p53-dependent apoptosis. 2007 Nov 1
173 17965021 The lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival. 2007 Dec 28 1
174 18246814 [Inhibition of tissue factor by siRNA enhances doxorubicin-induced apoptosis in human neuroblastoma]. 2007 Sep 1
175 16108013 Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin. 2006 Feb 15 1
176 16319532 Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms. 2006 Jan 1
177 16545138 CD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathways. 2006 Mar 18 1
178 16843435 p38 MAPK downregulates phosphorylation of Bad in doxorubicin-induced endothelial apoptosis. 2006 Sep 1 1
179 16909308 Requirement for pre-existing of p21 to prevent doxorubicin-induced apoptosis through inhibition of caspase-3 activation. 2006 Oct 3
180 16962673 The C-terminal CD47/IAP-binding domain of thrombospondin-1 prevents camptothecin- and doxorubicin-induced apoptosis in human thyroid carcinoma cells. 2006 Oct 1
181 17013758 Caspase-3 mediated feedback activation of apical caspases in doxorubicin and TNF-alpha induced apoptosis. 2006 Nov 4
182 17031387 Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin. 2006 Dec 1
183 17054846 [Adriamycin and mitomycin dose-dependently downregulate X-kinked inhibitor of apoptosis protein in human bladder cancer cells]. 2006 Jul 4 1
184 15578696 p53-R175H mutant gains new function in regulation of doxorubicin-induced apoptosis. 2005 Apr 10 1
185 15623433 Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation. 2005 Jan 2
186 15680309 Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide. 2005 Feb 11 1
187 15868924 Induction of tumor-specific cytotoxicity and apoptosis by doxorubicin. 2005 Mar-Apr 1
188 15985719 Induction of caspase 3 activity, bcl-2 bax and p65 gene expression modulation in human acute promyelocytic leukemia HL-60 cells by doxorubicin with amifostine. 2005 May-Jun 2
189 16086872 [Effect of inhibiting survivin expression with antisense oligodeoxynucleotides on sensitivity of hepatocellular carcinoma cell lines HepG2 and HepG2/ADM to adriamycin]. 2005 Aug 1
190 16139916 Folate receptor-mediated intracellular delivery of recombinant caspase-3 for inducing apoptosis. 2005 Nov 2 2
191 14657946 Caspase-3 activation in systemic anaplastic large-cell lymphoma. 2004 Jan 2
192 14736733 Ventricular nonmyocytes inhibit doxorubicin-induced myocyte apoptosis: involvement of endogenous endothelin-1 as a paracrine factor. 2004 May 1
193 14990581 Loss of MYC confers resistance to doxorubicin-induced apoptosis by preventing the activation of multiple serine protease- and caspase-mediated pathways. 2004 May 14 3
194 14995997 Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology. 2004 Feb 1
195 15054096 Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways. 2004 Jun 11 1
196 15174092 Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis. 2004 Aug 2
197 15233869 Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin-resistant human breast tumour (MCF-7/dox) cell-line. 2004 Jul 1
198 15557793 Involvement of ERK1/2 and p38 MAP kinase in doxorubicin-induced uPA expression in human RC-K8 lymphoma and NCI-H69 small cell lung carcinoma cells. 2004 2
199 15763945 Differential toxicity of anthracyclines on cultured endothelial cells. 2004 Sep-Dec 1
200 15981920 HPMA copolymer-bound doxorubicin induces apoptosis in human ovarian carcinoma cells by a Fas-independent pathway. 2004 May-Jun 1