Title : Retaining cytotoxic activity of anthrapyridone CO1 against multidrug resistant cells is related to the ability to induce concomitantly apoptosis and lysosomal death of leukaemia HL60/VINC and HL60/DOX cells.

Pub. Date : 2013 Jun

PMID : 23647679






1 Functional Relationships(s)
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1 Significantly lower caspase-3 and caspase-8 activity was also observed in the response of these cells to CO1 compared with DOX treatment. Doxorubicin caspase 3 Homo sapiens