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11792123 | CD40 ligation induces macrophage IL-10 and TNF-alpha production: differential use of the PI3K and p42/44 MAPK-pathways. | 2001 Nov 21 |
1 |
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10716639 | Ionizing radiation enhances double-strand-break repair in rapamycin-treated ataxia telangiectasia lymphoblasts. | 2000 Feb |
2 |
| 253 |
10753954 | Nitric oxide increases p21(Waf1/Cip1) expression by a cGMP-dependent pathway that includes activation of extracellular signal-regulated kinase and p70(S6k). | 2000 Apr 14 |
1 |
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10849422 | Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia. | 2000 Aug 18 |
2 |
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10971657 | Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro. | 2000 Sep |
1 |
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10981855 | Role and relation of p70 S6 and extracellular signal-regulated kinases in the phenotypic changes of hypertrophy of cardiac myocytes. | 2000 Sep |
1 |
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9873015 | Control of glycogen synthesis in cultured human muscle cells. | 1999 Jan 8 |
1 |
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9895282 | Insulin and insulin-like growth factor I up-regulate GLUT4 gene expression in fetal brown adipocytes, in a phosphoinositide 3-kinase-dependent manner. | 1999 Feb 1 |
1 |
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10029080 | Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells. | 1999 Feb 15 |
1 |
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10085104 | Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase/signal transducer and activator of transcription but not mitogen-activated protein kinase or p70 S6 kinase signaling. | 1999 Mar 26 |
1 |
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10200280 | Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein. | 1999 Apr 13 |
3 |
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10212283 | A potential role for extracellular signal-regulated kinases in prostaglandin F2alpha-induced protein synthesis in smooth muscle cells. | 1999 Apr 30 |
1 |
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10373522 | p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes. | 1999 Jul |
1 |
| 264 |
10446965 | Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K pathway in human pancreatic cancer cells. | 1999 Aug 1 |
2 |
| 265 |
10454535 | Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation. | 1999 Sep |
1 |
| 266 |
10455142 | Osmotic stress inhibits p70/85 S6 kinase through activation of a protein phosphatase. | 1999 Aug 27 |
4 |
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10480882 | p70 S6 kinase-mediated protein synthesis is a critical step for vascular endothelial cell proliferation. | 1999 Sep 17 |
3 |
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10490847 | Characterization of S6K2, a novel kinase homologous to S6K1. | 1999 Sep 9 |
1 |
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10490848 | Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt. | 1999 Sep 9 |
2 |
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10551813 | Hydrogen peroxide activates p70(S6k) signaling pathway. | 1999 Nov 12 |
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10567431 | Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro. | 1999 Nov 26 |
2 |
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10601276 | Insulin-like growth factor (IGF)-I regulates IGF-binding protein-5 gene expression through the phosphatidylinositol 3-kinase, protein kinase B/Akt, and p70 S6 kinase signaling pathway. | 1999 Dec 24 |
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9458731 | Signal transduction pathways involved in the regulation of protein synthesis by insulin in L6 myoblasts. | 1998 Jan |
1 |
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9528776 | A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo. | 1998 Apr |
1 |
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9531494 | Activation of S6 kinase in human neutrophils by calcium pyrophosphate dihydrate crystals: protein kinase C-dependent and phosphatidylinositol-3-kinase-independent pathways. | 1998 Apr 15 |
1 |
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9914383 | Inhibition of the Mr 70,000 S6 kinase pathway by rapamycin results in chromosome malsegregation in yeast and mammalian cells. | 1998 Dec |
2 |
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9045696 | The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. | 1997 Mar 7 |
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9109413 | PHAS-I phosphorylation in response to foetal bovine serum (FBS) is regulated by an ERK1/ERK2-independent and rapamycin-sensitive pathway in 3T3-L1 adipocytes. | 1997 Apr 7 |
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9175775 | Insulin stimulates p70 S6 kinase in the nucleus of cells. | 1997 May 29 |
1 |
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9202301 | Ganglioside GM1 activates the mitogen-activated protein kinase Erk2 and p70 S6 kinase in U-1242 MG human glioma cells. | 1997 Jul |
2 |
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9218810 | Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k. | 1997 Jun 16 |
2 |
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9242178 | Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70 S6 kinase. | 1997 Aug |
2 |
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1 |
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21528277 | Rapamycin inhibits substance P-induced protein synthesis and phosphorylation of PHAS-I (4E-BP1) and p70 S6 kinase (p70(S6K)) in human astrocytoma cells. | 1997 Oct |
1 |
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8603539 | The effects of the immunosuppressant rapamycin on the growth of rheumatoid arthritis (RA) synovial fibroblast. | 1996 Apr |
2 |
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8633019 | 4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase. | 1996 Apr 30 |
2 |
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8641294 | Regulation of translation elongation factor-2 by insulin via a rapamycin-sensitive signalling pathway. | 1996 May 1 |
1 |
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8752154 | Rapamycin inhibits constitutive p70s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells. | 1996 Sep 1 |
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8806686 | Rapamycin resistance in ataxia-telangiectasia. | 1996 Sep 5 |
1 |
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8887654 | The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases. | 1996 Nov |
1 |
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8939971 | Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes. | 1996 Nov 22 |
1 |
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7534292 | Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells. | 1995 Mar 10 |
1 |
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7566093 | Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway. | 1995 Sep 28 |
1 |
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7566123 | Control of p70 s6 kinase by kinase activity of FRAP in vivo. | 1995 Oct 5 |
2 |
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7629182 | Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway. | 1995 Aug 4 |
1 |
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7923380 | Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression. | 1994 Oct 7 |
2 |
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8344891 | The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sites. | 1993 Aug 5 |
1 |
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1380801 | Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells. | 1992 Aug 14 |
1 |