Title : Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt.

Pub. Date : 1999 Sep 9

PMID : 10490848






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Conceptual translation of the SRK cDNA revealed that the catalytic domain of SRK was highly homologous to that of p70S6K, and that the treatment of wortmannin or rapamycin strongly inhibited the phosphorylation and the activation of SRK, as in p70S6K. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens
2 Conceptual translation of the SRK cDNA revealed that the catalytic domain of SRK was highly homologous to that of p70S6K, and that the treatment of wortmannin or rapamycin strongly inhibited the phosphorylation and the activation of SRK, as in p70S6K. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens