Platinum

poly(ADP-ribose) polymerase 1 ; Homo sapiens







125 Article(s)
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51 32981695 Long-term safety in patients with recurrent ovarian cancer treated with niraparib versus placebo: Results from the phase III ENGOT-OV16/NOVA trial. 2020 Nov 1
52 33006584 PARP inhibition as frontline therapy in ovarian cancer. 2020 Sep 2
53 33068886 Newly diagnosed ovarian cancer: Which first-line treatment? 2020 Dec 4
54 33112397 Activity of Platinum-Based Chemotherapy in Patients With Advanced Prostate Cancer With and Without DNA Repair Gene Aberrations. 2020 Oct 1 2
55 33147530 A functional polymorphism in the poly(ADP-ribose) polymerase-1 gene is associated with platinum-based chemotherapeutic response and prognosis in epithelial ovarian cancer patients. 2020 Dec 3
56 33692936 Comparative Efficacy and Safety of PARP Inhibitors as Maintenance Therapy in Platinum Sensitive Recurrent Ovarian Cancer: A Network Meta-Analysis. 2020 1
57 29961768 Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer. 2019 Jan 2
58 30540581 Poly-ADP-ribosyl-polymerase inhibitor resistance mechanisms and their therapeutic implications. 2019 Feb 1
59 30672100 PARP inhibitors in ovarian cancer: Sensitivity prediction and resistance mechanisms. 2019 Apr 1
60 30797591 ERCC1-XPF deficiency is a predictor of olaparib induced synthetic lethality and platinum sensitivity in epithelial ovarian cancers. 2019 May 1
61 30895466 PARP Inhibitors and the Evolving Landscape of Ovarian Cancer Management: A Review. 2019 Jun 3
62 30919167 Targeting DNA Repair Defects for Precision Medicine in Prostate Cancer. 2019 Mar 27 1
63 31074636 Veliparib: a new therapeutic option in ovarian cancer? 2019 Jun 1
64 31091037 [New therapeutic strategies in advanced stage breast and tubo-ovarian cancers]. 2019 May 15 1
65 31194214 Immune Checkpoint and Poly(ADP-Ribose) Polymerase Inhibition for Recurrent Platinum-Resistant Ovarian and Metastatic Triple-Negative Breast Cancers. 2019 Aug 1 1
66 31478762 Olaparib in the treatment of ovarian cancer. 2019 Oct 1
67 31562799 Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer. 2019 Dec 19 1
68 31629204 Parp inhibitors as maintenance treatment in platinum sensitive recurrent ovarian cancer: An updated meta-analysis of randomized clinical trials according to BRCA mutational status. 2019 Nov 1
69 31685558 Antitumor activity of the poly(ADP-ribose) polymerase inhibitor rucaparib as monotherapy in patients with platinum-sensitive, relapsed, BRCA-mutated, high-grade ovarian cancer, and an update on safety. 2019 Nov 1
70 31738050 Synthesis, Cytotoxicity, and Mechanistic Investigation of Platinum(IV) Anticancer Complexes Conjugated with Poly(ADP-ribose) Polymerase Inhibitors. 2019 Dec 2 3
71 31907114 Verapamil enhances the sensitivity of oxaliplatin to tumor cells by influencing the PARP pathway. 2019 Dec 1 1
72 29396858 Recapitulating the clinical scenario of BRCA-associated pancreatic cancer in pre-clinical models. 2018 Jul 1 1
73 29397193 The poly (ADP ribose) polymerase inhibitor niraparib: Management of toxicities. 2018 Apr 1
74 29750420 Latest clinical evidence and further development of PARP inhibitors in ovarian cancer. 2018 Jun 1 2
75 29871906 PARP Inhibitors in Ovarian Cancer: A Trailblazing and Transformative Journey. 2018 Sep 1 1
76 30067614 Management of newly diagnosed or recurrent ovarian cancer. 2018 Jun 1
77 30080919 Using PARP Inhibitors in Advanced Ovarian Cancer. 2018 Jul 15 1
78 30082520 Association of Base Excision Repair Gene Polymorphisms with the Response to Chemotherapy in Advanced Non-Small Cell Lung Cancer. 2018 Aug 20 1
79 30228165 Defective DNA repair in hereditary ovarian cancers: Implications for therapy. 2018 Nov 1 1
80 30278221 PARP inhibition in platinum-based chemotherapy: Chemopotentiation and neuroprotection. 2018 Nov 3
81 28471247 The safety of antiangiogenic agents and PARP inhibitors in platinum-sensitive recurrent ovarian cancer. 2017 Jun 1
82 28487881 Whole-genome sequencing identifies homozygous BRCA2 deletion guiding treatment in dedifferentiated prostate cancer. 2017 May 2
83 29109859 Candidate synthetic lethality partners to PARP inhibitors in the treatment of ovarian clear cell cancer. 2017 Nov 2
84 29232464 Treatment of recurrent ovarian cancer. 2017 Nov 1 1
85 26693899 Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer. 2016 Jan 1
86 26984416 What Is the Place of PARP Inhibitors in Ovarian Cancer Treatment? 2016 May 2
87 27127105 PARP Inhibitors in Epithelial Ovarian Cancer: State of Art and Perspectives of Clinical Research. 2016 May 1
88 27155850 Assessment of PARP protein expression in epithelial ovarian cancer by ELISA pharmacodynamic assay and immunohistochemistry. 2016 Sep 2
89 27655641 Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma. 2016 Nov 8 1
90 27736844 PARP inhibitors for BRCA1/2-mutated and sporadic ovarian cancer: current practice and future directions. 2016 Nov 8 1
91 27756336 Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study. 2016 Oct 19 2
92 27821802 Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review. 2016 Dec 20 1
93 27884198 Use of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinic. 2016 Nov 24 1
94 25304989 Clinical outcomes in pancreatic adenocarcinoma associated with BRCA-2 mutation. 2015 Feb 1
95 25779564 Poly (ADP-ribose) polymerase inhibitors: recent advances and future development. 2015 Apr 20 2
96 25991068 Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer. 2015 May 20 1
97 26206420 An overview of early investigational therapies for chemoresistant ovarian cancer. 2015 4
98 26269716 Informative gene network for chemotherapy-induced peripheral neuropathy. 2015 1
99 26374559 Clinical Trials of Poly(ADP-Ribose) Polymerase Inhibitors for Cancer Therapy: A Review. 2015 1
100 26646960 [Individualized treatment for ovarian cancer may become possible]. 2015 Dec 8 1