Pub. Date : 2022 Mar
PMID : 35124372
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Poly(ADP-Ribose) polymerase 1 (PARP1) is an enzyme crucial for repairing DNA damage induced by platinum compounds, which undermines the effectiveness of platinum-based chemotherapy. | Platinum | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 2 | Poly(ADP-Ribose) polymerase 1 (PARP1) is an enzyme crucial for repairing DNA damage induced by platinum compounds, which undermines the effectiveness of platinum-based chemotherapy. | Platinum | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 3 | Poly(ADP-Ribose) polymerase 1 (PARP1) is an enzyme crucial for repairing DNA damage induced by platinum compounds, which undermines the effectiveness of platinum-based chemotherapy. | Platinum | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 4 | Poly(ADP-Ribose) polymerase 1 (PARP1) is an enzyme crucial for repairing DNA damage induced by platinum compounds, which undermines the effectiveness of platinum-based chemotherapy. | Platinum | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 5 | Our finding that the TOPBP1/PARP1 pathway facilitates acquisition of oxaliplatin resistance uncovers a novel mechanism underlying platinum-based chemotherapy resistance in gastric cancer that may be utilized for developing effective therapeutic strategies. | Platinum | poly(ADP-ribose) polymerase 1 | Homo sapiens |