Title : Anticancer Activity of Platinum (II) Complex with 2-Benzoylpyridine by Induction of DNA Damage, S-Phase Arrest, and Apoptosis.

Pub. Date : 2020

PMID : 31721706






3 Functional Relationships(s)
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1 Pt(II)-Bpy induced DNA damage, which was demonstrated through a marked increase in the expression of cleaved-poly (ADP ribose) polymerase (PARP) and gamma-H2A histone family member X and a decrease in PARP expression. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens
2 Pt(II)-Bpy induced DNA damage, which was demonstrated through a marked increase in the expression of cleaved-poly (ADP ribose) polymerase (PARP) and gamma-H2A histone family member X and a decrease in PARP expression. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens
3 Pt(II)-Bpy induced DNA damage, which was demonstrated through a marked increase in the expression of cleaved-poly (ADP ribose) polymerase (PARP) and gamma-H2A histone family member X and a decrease in PARP expression. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens