Title : Retrospective review of outcomes in patients with DNA-damage repair related pancreatic cancer.

Pub. Date : 2020

PMID : 32793315






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1 Background: Patients with DNA-damage response genes (DDR)-related pancreas cancer (BRCA1/2 or other DNA-damage related genes) may have improved outcomes secondary to increased sensitivity to DNA-damaging drugs (platinum chemotherapy/ poly ADP ribose polymerase (PARP)-inhibitors). Platinum poly(ADP-ribose) polymerase 1 Homo sapiens