Platinum

poly(ADP-ribose) polymerase 1 ; Homo sapiens







125 Article(s)
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101 26669450 PARP inhibitors in ovarian cancer: Clinical evidence for informed treatment decisions. 2015 Dec 15 1
102 24189460 Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer. 2014 Jan 1 1
103 24361480 Platinated benzonaphthyridone is a stronger inhibitor of poly(ADP-ribose) polymerase-1 and a more potent anticancer agent than is the parent inhibitor. 2014 Jan 2
104 24607283 PARP inhibitors in ovarian cancer: current status and future promise. 2014 May 1
105 24761869 Expression of ERCC1, MSH2 and PARP1 in non-small cell lung cancer and prognostic value in patients treated with platinum-based chemotherapy. 2014 2
106 24882434 Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. 2014 Jul 1
107 25124282 Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer. 2014 Dec 1
108 22983827 Association between polymorphisms of XRCC1 and ADPRT genes and ovarian cancer survival with platinum-based chemotherapy in Chinese population. 2013 Jan 2
109 23275151 PARP inhibition selectively increases sensitivity to cisplatin in ERCC1-low non-small cell lung cancer cells. 2013 Apr 1
110 23410825 PARP1 impact on DNA repair of platinum adducts: preclinical and clinical read-outs. 2013 May 5
111 23479135 Polymorphisms in the base excision repair pathway modulate prognosis of platinum-based chemotherapy in advanced non-small cell lung cancer. 2013 May 1
112 23640560 Effects of poly (ADP-ribosyl) polymerase (PARP) inhibitor on cisplatin resistance & proliferation of the ovarian cancer C13* cells. 2013 Mar 2
113 22504675 [Clinical development of PARP inhibitors]. 2012 Apr 1
114 22869732 BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation. 2012 Aug 21 2
115 22926640 Clinical trials and future potential of targeted therapy for ovarian cancer. 2012 Oct 1
116 21370912 Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA. 2011 Apr 14 1
117 21819606 Drug therapy for hereditary cancers. 2011 Aug 6 1
118 20406929 Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. 2010 May 20 1
119 20550106 Recognition of platinum-DNA damage by poly(ADP-ribose) polymerase-1. 2010 Jul 27 6
120 20940192 Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer. 2010 Nov 20 1
121 19053130 Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. 2009 Jan 5 1
122 18977144 Poly(ADP-ribose) polymerase-1 activity facilitates the dissociation of nuclear proteins from platinum-modified DNA. 2008 Dec 1 4
123 17332279 Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology. 2007 Mar 1 1
124 16787355 Poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide enhances apoptosis induction by platinum complexes in cisplatin-resistant tumor cells. 2006 Jan 2
125 9380409 The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. 1997 Sep 25 1