Title : [Inhibition of proliferation of adult T-cell leukemia cells by celastrol].

Pub. Date : 2018 Sep 25

PMID : 30255683






2 Functional Relationships(s)
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1 With the increase of the concentration of celastrol, the ratio of Bax/Bcl-2 protein was up-regulated. celastrol BCL2 apoptosis regulator Homo sapiens
2 Taken together, these results indicated that celastrol effectively inhibited the proliferation of adult T-cell leukemia cells by regulating the expression of Bcl-2 family protein, and induced cell apoptosis by activating Caspase dependent pathway. celastrol BCL2 apoptosis regulator Homo sapiens