Pub. Date : 2018 Sep 25
PMID : 30255683
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | With the increase of the concentration of celastrol, the ratio of Bax/Bcl-2 protein was up-regulated. | celastrol | BCL2 apoptosis regulator | Homo sapiens |
2 | Taken together, these results indicated that celastrol effectively inhibited the proliferation of adult T-cell leukemia cells by regulating the expression of Bcl-2 family protein, and induced cell apoptosis by activating Caspase dependent pathway. | celastrol | BCL2 apoptosis regulator | Homo sapiens |