Title : Celastrol inhibits chondrosarcoma proliferation, migration and invasion through suppression CIP2A/c-MYC signaling pathway.

Pub. Date : 2017 May

PMID : 28522217






1 Functional Relationships(s)
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1 In addition, celastrol inhibited the expression of CIP2A, c-MYC, and suppressed apoptotic proteins BAX and caspase-8 in human CS cells, on the other hand, it induced the expression of antiapoptotic protein Bcl-2. celastrol BCL2 apoptosis regulator Homo sapiens