Title : Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid.

Pub. Date : 2006 Nov 15

PMID : 16984800






1 Functional Relationships(s)
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1 Celastrol prevented not only LPS-induced mRNA expression of iNOS and TNF-alpha, but also TNF-alpha-induced Bfl-1/A1 expression, a prosurvival Bcl-2 homologue. celastrol BCL2 apoptosis regulator Homo sapiens