Title : Cytotoxic effect of celastrol alone or in combination with paclitaxel on anaplastic thyroid carcinoma cells.

Pub. Date : 2017 May

PMID : 28459364






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In conclusion, our results suggest that celastrol induces cytotoxicity through involvement of Bcl2 family proteins and death receptor, and modulation of phospho-NF-kappaB, Akt, and mitogen-activated protein kinase in association with endoplasmic reticulum stress and reactive oxygen species production in anaplastic thyroid carcinoma cells. celastrol BCL2 apoptosis regulator Homo sapiens