Fluorouracil

BCL2 apoptosis regulator ; Homo sapiens







127 Article(s)
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101 16407826 Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL. 2006 May 25 1
102 16412276 Inhibition of Bcl-2 expression by a novel tumor-specific RNA interference system increases chemosensitivity to 5-fluorouracil in Hela cells. 2006 Feb 3
103 16557594 Transcriptional profiling of MCF7 breast cancer cells in response to 5-Fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53. 2006 Sep 1 1
104 16596200 hRFI overexpressed in HCT116 cells modulates Bcl-2 family proteins when treated with 5-fluorouracil. 2006 May 4
105 16603448 Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells. 2006 Jan 4
106 17287894 Schedule-dependent cytotoxicity of 5-fluorouracil and irinotecan in a colon cancer cell line. 2006 Dec 1
107 15365767 Docosahexaenoic acid enhances the susceptibility of human colorectal cancer cells to 5-fluorouracil. 2005 Jan 1
108 16168113 Addition of 5-fluorouracil to doxorubicin-paclitaxel sequence increases caspase-dependent apoptosis in breast cancer cell lines. 2005 1
109 16332177 Enhanced sensitivity of human hepatoma cells to 5-fluorouracil by small interfering RNA targeting Bcl-2. 2005 Dec 6
110 15124184 5-Fluorouracil enhances apoptosis sensitivity of T lymphocytes mediated by CD3 epsilon. 2004 May-Jun 1
111 15177426 Chemosensitization of breast carcinoma cells with the use of bcl-2 antisense oligodeoxynucleotide. 2004 Jun 3
112 15467752 Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway. 2004 Oct 28 1
113 12469202 Bcl-2 in cancer and normal tissue cells as a prediction marker of response to 5-fluorouracil. 2003 Jan 2
114 12915131 Ha-ras overexpression mediated cell apoptosis in the presence of 5-fluorouracil. 2003 Aug 15 2
115 11920608 Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status. 2002 Apr 1 3
116 12138244 Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes. 2002 2
117 11044365 Bcl-2/Bax protein ratio predicts 5-fluorouracil sensitivity independently of p53 status. 2000 Nov 7
118 10470656 Drug-induced apoptosis and p53, BCL-2 and BAX expression in breast cancer tissues in vivo and in fibroblast cells in vitro. 1999 Jul 1
119 10499633 Antagonistic interplay between antimitotic and G1-S arresting agents observed in experimental combination therapy. 1999 Sep 1
120 10697613 Thymidine phosphorylase expression in invasive carcinoma: correlations with clinicopathologic variables and in vitro chemosensitivity to 5-fluorouracil. 1999 Nov-Dec 1
121 9792140 5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins. 1998 Oct 6
122 11819336 Transduction of Fas gene or Bcl-2 antisense RNA sensitizes cultured drug resistant gastric cancer cells to chemotherapeutic drugs. 1998 Oct 1
123 9020491 Bcl-2 expression and response to chemotherapy in colorectal adenocarcinomas. 1997 2
124 9209521 Effect of preoperative 5-fluorouracil on apoptosis of advanced gastric cancer. 1997 Jun 2
125 14646558 5-Fluorouracil (5-FU) induced apoptosis in gastric cancer cell lines: role of the p53 gene. 1997 3
126 9815973 Expression of bcl-2 protein predicts efficacy of adjuvant treatments in operable node-positive breast cancer. 1995 Feb 1
127 7654318 Antiapoptosis potential of bcl-2 oncogene by dephosphorylation. 1994 Nov-Dec 2