| 51 |
25236742 | Binge alcohol promotes hypoxic liver injury through a CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans. | 2014 Dec |
2 |
| 52 |
25462060 | Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling. | 2014 |
2 |
| 53 |
25462064 | Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness. | 2014 |
10 |
| 54 |
22940046 | CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease. | 2013 Feb |
3 |
| 55 |
23126531 | Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. | 2013 Apr |
1 |
| 56 |
23274499 | Ethanol potentiates hepatitis B virus replication through oxidative stress-dependent and -independent transcriptional activation. | 2013 Feb 1 |
1 |
| 57 |
23352969 | Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure. | 2013 Mar 14 |
3 |
| 58 |
23400917 | Cytochrome P450 2E1: its clinical aspects and a brief perspective on the current research scenario. | 2013 |
3 |
| 59 |
23400919 | The role of cytochrome P450 2E1 in ethanol-mediated carcinogenesis. | 2013 |
3 |
| 60 |
23400922 | CYP2E1-catalyzed alcohol metabolism: role of oxidant generation in interferon signaling, antigen presentation and autophagy. | 2013 |
4 |
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23400924 | The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system. | 2013 |
1 |
| 62 |
23471973 | Human cytochrome P450 2E1 mutations that alter mitochondrial targeting efficiency and susceptibility to ethanol-induced toxicity in cellular models. | 2013 May 3 |
1 |
| 63 |
23534720 | Functional PstI/RsaI polymorphisms in the CYP2E1 gene among south Indian populations. | 2013 |
1 |
| 64 |
23660503 | Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. | 2013 Jul 15 |
9 |
| 65 |
23892124 | Alcoholic lung injury: metabolic, biochemical and immunological aspects. | 2013 Oct 24 |
2 |
| 66 |
24025710 | Iron-mediated effect of alcohol on hepatocyte differentiation in HepaRG cells. | 2013 Nov 25 |
1 |
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24151610 | Polymorphisms in the human cytochrome P450 and arylamine N-acetyltransferase: susceptibility to head and neck cancers. | 2013 |
1 |
| 68 |
24288753 | CYP2E1 gene promoter polymorphism -1293G>C increases the risk of essential hypertension in men with alcohol abuse. | 2013 Oct |
2 |
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24307790 | Alcoholism and liver disease in Mexico: genetic and environmental factors. | 2013 Nov 28 |
1 |
| 70 |
21895718 | Genetic polymorphisms of genes coding to alcohol-metabolizing enzymes in western Mexicans: association of CYP2E1*c2/CYP2E1*5B allele with cirrhosis and liver function. | 2012 Mar |
3 |
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22028977 | CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases. | 2012 |
1 |
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22100631 | Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesis. | 2012 Feb |
2 |
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22309822 | In vitro evidence for chronic alcohol and high glucose mediated increased oxidative stress and hepatotoxicity. | 2012 Jun |
1 |
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22331481 | Alcohol, genetics and risk of breast cancer in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. | 2012 Jun |
1 |
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22385180 | Molecular dynamics simulations of CYP2E1. | 2012 Mar |
1 |
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22396533 | Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes. | 2012 May 4 |
3 |
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22560290 | A comparison of Val81Met and other polymorphisms of alcohol metabolising genes in patients and controls in Northern Spain. | 2012 Aug |
1 |
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22577853 | Association between in vivo alcohol metabolism and genetic variation in pathways that metabolize the carbon skeleton of ethanol and NADH reoxidation in the alcohol challenge twin study. | 2012 Dec |
1 |
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22699086 | Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with baicalin. | 2012 Sep |
2 |
| 80 |
22871069 | Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes. | 2012 Nov |
2 |
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22954124 | Association of genetic polymorphisms of aldehyde dehydrogenase-2 and cytochrome P450 2E1-RsaI and alcohol consumption with oral squamous cell carcinoma. | 2012 Aug |
1 |
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20715111 | Ethanol-mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA-lesions. | 2011 Feb 1 |
2 |
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20843640 | Induction of blood lymphocyte cytochrome P450 2E1 in early stage alcoholic liver cirrhosis. | 2011 Feb |
2 |
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20958328 | The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis. | 2011 Jan |
4 |
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21039635 | Effect of alcohol on drug efflux protein and drug metabolic enzymes in U937 macrophages. | 2011 Jan |
3 |
| 86 |
21150132 | Progression of alcoholic and non-alcoholic steatohepatitis: common metabolic aspects of innate immune system and oxidative stress. | 2011 |
1 |
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21360299 | APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson's disease in a Japanese population. | 2011 Sep |
1 |
| 88 |
21402122 | Gender-specific interactions between alcohol metabolism genes and severity of quantitative alcohol-related-traits in a Tibetan population. | 2011 May 9 |
1 |
| 89 |
21414402 | Elevated glutathione level does not protect against chronic alcohol mediated apoptosis in recombinant human hepatoma cell line VL-17A over-expressing alcohol metabolizing enzymes--alcohol dehydrogenase and Cytochrome P450 2E1. | 2011 Jun |
3 |
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21705789 | Genetic polymorphisms of ADH1C and CYP2E1 and risk of oral squamous cell carcinoma. | 2011 Oct |
1 |
| 91 |
21940907 | Joint effects of alcohol consumption and polymorphisms in alcohol and oxidative stress metabolism genes on risk of head and neck cancer. | 2011 Nov |
3 |
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19798529 | CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction. | 2010 Jun |
1 |
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19860798 | Polymorphisms of alcohol metabolizing enzymes in indigenous Mexican population: unusual high frequency of CYP2E1*c2 allele. | 2010 Jan |
2 |
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20051262 | Biochemical mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) cells. | 2010 Mar 2 |
1 |
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20118189 | Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors. | 2010 May |
1 |
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20364586 | [Association between aldehyde dehydrogenase-2/cytochrome P450 2E1 genetic polymorphism and habit of alcohol drinking and the susceptibility of hepatocellular carcinoma]. | 2010 Jan |
2 |
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20401433 | Genetic polymorphism of alcohol-metabolizing enzyme and alcohol dependence in Polish men. | 2010 Mar |
5 |
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20598484 | Distribution of ADH1B, ALDH2, CYP2E1 *6, and CYP2E1 *7B genotypes in Turkish population. | 2010 Aug |
1 |
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20723539 | IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways. | 2010 Nov 15 |
2 |
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20813101 | Formation of acetaldehyde-derived DNA adducts due to alcohol exposure. | 2010 Dec 5 |
1 |