Title : Elevated glutathione level does not protect against chronic alcohol mediated apoptosis in recombinant human hepatoma cell line VL-17A over-expressing alcohol metabolizing enzymes--alcohol dehydrogenase and Cytochrome P450 2E1.

Pub. Date : 2011 Jun

PMID : 21414402






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ethanol-inducible Cytochrome P450 2E1 (CYP2E1) plays a critical role in alcohol mediated oxidative stress due to its ability to metabolize ethanol. Alcohols cytochrome P450 family 2 subfamily E member 1 Homo sapiens
2 Ethanol-inducible Cytochrome P450 2E1 (CYP2E1) plays a critical role in alcohol mediated oxidative stress due to its ability to metabolize ethanol. Alcohols cytochrome P450 family 2 subfamily E member 1 Homo sapiens
3 In the present study, using the recombinant human hepatoma cell line VL-17A that over-expresses the alcohol metabolizing enzymes-alcohol dehydrogenase (ADH) and CYP2E1; and control HepG2 cells, the mechanism and mode of cell death due to chronic ethanol exposure were studied. Alcohols cytochrome P450 family 2 subfamily E member 1 Homo sapiens