Pub. Date : 2011 Nov
PMID : 21940907
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Four SNPs in alcohol metabolism genes interacted additively with alcohol consumption: ALDH2 rs2238151, ADH1B rs1159918, ADH7 rs1154460, and CYP2E1 rs2249695. | Alcohols | cytochrome P450 family 2 subfamily E member 1 | Homo sapiens |
| 2 | Four SNPs in alcohol metabolism genes interacted additively with alcohol consumption: ALDH2 rs2238151, ADH1B rs1159918, ADH7 rs1154460, and CYP2E1 rs2249695. | Alcohols | cytochrome P450 family 2 subfamily E member 1 | Homo sapiens |
| 3 | CONCLUSIONS AND IMPACT: Previously unreported associations of SNPs in ALDH2, CYP2E1, GPX2, SOD1, and SOD2 with SCCHN and subsite tumors provide evidence that alterations in alcohol and oxidative stress pathways influence SCCHN carcinogenesis and warrant further investigation. | Alcohols | cytochrome P450 family 2 subfamily E member 1 | Homo sapiens |